Jorge Darcourt, MD

Assistant Professor of Clinical Medicine in Oncology, Institute for Academic Medicine
Assistant Clinical Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Dr. Jorge Darcourt earned his medical degree at the Universidad de Buenos Aires in Argentina in 1999. He completed his residency at The University of Texas Health Science at Houston and his fellowship at Baylor College of Medicine in Hematology and Oncology. He currently serves as the medical director of the Methodist Sugar Land Infusion Center as well as chairman for the Department of Medicine. 

Description of Research

The current research initiative is in targeted therapies for breast malignancies. The research proposal is to produce preclinical data that support the combination of enzalutamide or abiraterone in combination with everolimus to develop a pharmaceutical-sponsored phase I/II clinical trial of the combination of these agents in ER-/AR+ metastatic breast cancer and to add this regimen to exemestane for the treatment of ER+/AR+ metastatic breast cancer.

Areas Of Expertise

Breast cancer Metastatic breast cancer Everolimus

The role of immune reconstitution inflammatory syndrome in AIDS-related Cryptococcus neoformans disease in the era of highly active antiretroviral therapy
Shelburne, SA , Darcourt, J, White, AC, Greenberg, SB, Hamill, RJ, Atmar, RL & Visnegarwala, F 2005, Clinical Infectious Diseases, vol 40, no. 7, pp. 1049-1052. DOI:

Incidence and risk factors for immune reconstitution inflammatory syndrome during highly active antiretroviral therapy
Shelburne, SA, Visnegarwala, F, Darcourt, J, Graviss, EA, Giordano, TP, White, AC & Hamill, RJ 2005, AIDS, vol 19, no. 4, pp. 399-406.

Changes in metabolic profile among antiretroviral-naive patients initiating protease inhibitor versus non-protease inhibitor containing HAART regimens [3]
Visnegarwala, F, Darcourt, J, Sajja, P, Menon, V, Ong, O, Maldonado, M & White, AC 2003, Journal of Acquired Immune Deficiency Syndromes, vol 33, no. 5, pp. 653-655. DOI: