Yi Jonathan Zhang, MD

Assistant Professor of Clinical Neurosurgery, Institute for Academic Medicine
Houston Methodist
Weill Cornell Medical College

Education & Training

Clinical Fellowship , Emory University
Residency , Emory University
Internship , Emory University
MD , Baylor College of Medicine

Subarachnoid hemorrhage - Induced block of cerebrospinal fluid flow: Role of brain coagulation factor III (tissue factor)
Golanov, EV, Bovshik, E, Wong, K, Pautler, RG, Foster, C, Federley, R, Zhang, YJ, Mancuso, J, Wong, ST & Britz, GW 2017, Journal of Cerebral Blood Flow and Metabolism. DOI:

Relationships and redundancies of selected hemodynamic and structural parameters for characterizing virtual treatment of cerebral aneurysms with flow diverter devices
Karmonik, C, Anderson, JR, Beilner, J, Ge, JJ, Partovi, S, Klucznik, RP, Diaz, O, Zhang, YJ, Britz, GW, Grossman, RG, Lv, N & Huang, Q 2015, Journal of Biomechanics. DOI:

Comprehensive Overview of Contemporary Management Strategies for Cerebral Aneurysms
Manhas, A, Nimjee, SM, Agrawal, A, Zhang, J, Diaz, O, Zomorodi, AR, Smith, T, Powers, CJ, Sauvageau, E, Klucznik, RP, Ferrell, A, Golshani, K, Stieg, PE & Britz, GW 2015, World Neurosurgery, vol 84, no. 4, pp. 1147-1160. DOI:

Delayed Hydrocephalus and Perianeurysmal Cyst Formation After Stent-Assisted Coil Embolization of a Large, Unruptured Basilar Apex Aneurysm: A Case Report and Literature Review
Barber, SM, Al-Zubidi, N, Diaz, OM, Zhang, YJ & Lee, AG 2015, Asia-Pacific Journal of Ophthalmology, vol 3, no. 6, pp. 354-60. DOI:

Quantitative comparison of hemodynamic parameters from steady and transient CFD simulations in cerebral aneurysms with focus on the aneurysm ostium
Karmonik, C , Diaz, O , Klucznik, R , Grossman, RG , Zhang, YJ , Britz, G, Lv, N & Huang, Q 2015, Journal of NeuroInterventional Surgery, vol 7, no. 5, pp. 367-372. DOI:

Brain aneurysms
Zhang, YJ, Desai, V, Diaz, O, Klucznik, RP & Britz, G 2015, . in Emergency Approaches to Neurosurgical Conditions. Springer International Publishing, pp. 89-101. DOI:

Magnetic resonance imaging as a tool to assess reliability in simulating hemodynamics in cerebral aneurysms with a dedicated computational fluid dynamics prototype: preliminary results
Karmonik, C , Zhang, YJ , Diaz, O , Klucznik, R, Partovi, S, Grossman, RG & Britz, GW 2014, Cardiovascular diagnosis and therapy, vol 4, no. 2, pp. 207-12. DOI:

Modern interventional management of stroke
Ferrell, AS, Zhang, YJ, Diaz, O, Klucznik, R & Britz, GW 2014, Houston Methodist DeBakey Cardiovascular Journal, vol 10, no. 2, pp. 105-110.

Erratum: Combinational targeting offsets antigen escape and enhances effector functions of adoptively transferred T cells in glioblastoma (Molecular Therapy (2012) 21 (2087-2101) DOI: 10.1038/mt.2013.185)
Hegde, M, Corder, A, Chow, KK, Mukherjee, M, Ashoori, A, Kew, Y, Zhang, YJ, Baskin, DS, Merchant, FA, Brawley, VS, Byrd, TT, Krebs, S, Wu, MF, Liu, H, EHeslop, H, Gottschalk, S, Yvon, E & Ahmed, N 2014, Molecular Therapy, vol 22, no. 5. DOI:

Middle cerebral artery aneurysms: A single-center series comparing endovascular and surgical treatment
Diaz, OM, Rangel-Castilla, L, Barber, S, Mayo, RC, Klucznik, R & Zhang, YJ 2014, World Neurosurgery, vol 81, no. 2, pp. 322-329. DOI:

Combinational Targeting offsets antigen escape and enhances effector functions of adoptively transferred T cells in glioblastoma
Hegde, M, Corder, A, Chow, KK, Mukherjee, M, Ashoori, A, Kew, Y, Zhang, YJ, Baskin, DS, Merchant, FA, Brawley, VS, Byrd, TT, Krebs, S, Wu, MF, Liu, H, Heslop, HE, Gottachalk, S, Yvon, E & Ahmed, N 2013, Molecular Therapy, vol 21, no. 11, pp. 2087-2101. DOI:

Quantification of speed-up and accuracy of multi-CPU computational flow dynamics simulations of hemodynamics in a posterior communicating artery aneurysm of complex geometry
Karmonik, C, Yen, C, Gabriel, E, Partovi, S, Horner, M, Zhang, YJ, Klucznik, RP, Diaz, O & Grossman, RG 2013, Journal of NeuroInterventional Surgery, vol 5, no. SUPPL.3. DOI:

The role of endoscopic third ventriculostomy in the treatment of communicating hydrocephalus
Rangel-Castilla, L, Barber, S & Zhang, YJ 2012, World Neurosurgery, vol 77, no. 3-4, pp. 555-560. DOI:

Neuroendoscopic diagnosis of central nervous system histoplasmosis with basilar arachnoiditis
Rangel-Castilla, L, Hwang, SW, White, AC & Zhang, YJ 2012, World Neurosurgery, vol 77, no. 2. DOI:

Hydrocephalus in Wegener's granulomatosis: Neuroendoscopic findings and management
Rangel-Castilla, L, Barber, SM & Zhang, YJ 2011, Journal of Rheumatology, vol 38, no. 10, pp. 2277-2278. DOI:

Desmoplastic non-infantile ganglioglioma in late adulthood
Rangel-Castilla, L, Kew, Y, Powell, S & Zhang, YJ 2011, Journal of Neuro-Oncology, vol 103, no. 3, pp. 733-737. DOI:

Multi-modality imaging for the simulation of cerebral aneurysm blood flow dynamics
Karmonik, C , Zhang, YJ & Grossman, RG 2010, . in Computational Surgery and Dual Training. Springer US, pp. 233-248. DOI:

HER2-specific T cells target primary glioblastoma stem cells and induce regression of autologous experimental tumors
Ahmed, N, Salsman, VS, Kew, Y, Shaffer, D, Powell, S, Zhang, YJ, Grossman, RG, Heslop, HE & Gottschalk, S 2010, Clinical Cancer Research, vol 16, no. 2, pp. 474-485. DOI:

Dissemination of prostate adenocarcinoma to the skull base mimicking giant trigeminal schwannoma: Anatomic relevance of the extradural neural axis component
Gasco, J, Kew, Y, Livingston, A, Rose, J & Zhang, YJ 2009, Skull Base, vol 19, no. 6, pp. 425-430. DOI:

Suppression of post-ischemic-induced Fos protein expression by an antisense oligonucleotide to c-fos mRNA leads to increased tissue damage
Zhang, Y, Widmayer, MA, Zhang, B, Cui, JK & Baskin, DS 1999, Brain Research, vol 832, no. 1-2, pp. 112-117. DOI: