John Buergler, MD

Associate Professor of Clinical Cardiology, Institute for Academic Medicine
Assistant Clinical Member, Research Institute
Assistant Professor, Weill Cornell Medical College
Houston Methodist
Weill Cornell Medical College



Dr. Buergler joined the Section of Cardiology in the Department of Medicine at the Baylor College of Medicine in Houston, Texas in 1999 as an Assistant Professor of Medicine, a position held until 2005 when he joined The Methodist Hospital Physician Organization. As a clinical interventional cardiologist, Dr. Buergler has become an expert in alcohol septal ablation, a therapeutic procedure used to relieve the dynamic outflow track obstruction in patients with hypertrophic obstructive cardiomyopathy.

Description of Research

Dr. Buergler´s research interest is in the development of better techniques for improving the results of alcohol septal ablation, including the use of magnetic-guided stereotaxis catheterization.

Areas Of Expertise

Hypertrophic obstructive cardiomyopathy Alcohol septal ablation Stereotaxis
Education & Training

, Baylor College of Medicine
, Washington University Medical Center
, University of Chicago School of Medicine

Vortex Formation Time in Patients with Hypertrophic Cardiomyopathy
Maragiannis, D, Schutt, R, Alvarez, P, Chin, K, Buergler, J, Little, S, Shah, D & Nagueh, S 2015, AHA-Scientific Sessions, Orlando, United States, 11/7/15, .

The Brockenbrough-Braunwald-Morrow sign
Trevino, AR & Buergler, J 2014, Methodist DeBakey Cardiovascular Journal, vol 10, no. 1, pp. 34-37.

A mid-ventricular variant of Takotsubo cardiomyopathy.
Velankar, P & Buergler, J 2012, Houston Methodist DeBakey Cardiovascular Journal, vol 8, no. 3, pp. 37-39.

Early post-operative dysfunction of a mechanical aortic valve.
Shah, T, Ramlawi, B, Buergler, J, Chang, S & Little, SH 2012, Houston Methodist DeBakey Cardiovascular Journal, vol 8, no. 2, pp. 54-55.

Alcohol septal ablation for the treatment of hypertrophic obstructive cardiomyopathy: A multicenter north american registry
Nagueh, SF, Groves, BM, Schwartz, L, Smith, KM, Wang, A, Bach, RG, Nielsen, C, Leya, F, Buergler, JM, Rowe, SK, Woo, A, Maldonado, YM & Spencer, WH 2011, Journal of the American College of Cardiology, vol 58, no. 22, pp. 2322-2328. DOI:

Balancing hemostasis and thrombosis in interventional vascular medicine and surgery.
Buergler, JM & Kleiman, NS 2011, Houston Methodist DeBakey Cardiovascular Journal, vol 7, no. 4, pp. 19-23.

The importance of atrial pacing during alcohol septal ablation
Buergler, JM & Nagueh, SF 2010, Journal of Invasive Cardiology, vol 22, no. 3, pp. 146-147.

Impact of computerized dosing on eptifibatide-associated bleeding and mortality
Putney, DR, Kleiman, NS, Fromm, RE & Buergler, JM 2009, American Heart Journal, vol 158, no. 6, pp. 1018-1023. DOI:

Delayed Untwisting. The Mechanistic Link Between Dynamic Obstruction and Exercise Tolerance in Patients With Hypertrophic Obstructive Cardiomyopathy
Wang, J, Buergler, JM, Veerasamy, K, Ashton, YP & Nagueh, SF 2009, Journal of the American College of Cardiology, vol 54, no. 14, pp. 1326-1334. DOI:

Alcohol septal ablation and the Brockenbrough-Braunwald phenomenon
Soon, CY & Buergler, JM 2008, Catheterization and Cardiovascular Interventions, vol 72, no. 7, pp. 1016-1024. DOI:

Initial experience with alcohol septal ablation using a novel magnetic navigation system
Buergler, JM, Alam, S, Spencer, W, Kleiman, NS, Melendez, Y, Franklin, J & Nagueh, SF 2007, Journal of Interventional Cardiology, vol 20, no. 6, pp. 559-563. DOI:

Outcome of Surgical Myectomy After Unsuccessful Alcohol Septal Ablation for the Treatment of Patients With Hypertrophic Obstructive Cardiomyopathy
Nagueh, SF , Buergler, JM , Quinones, MA, Spencer, WH & Lawrie, GM 2007, Journal of the American College of Cardiology, vol 50, no. 8, pp. 795-798. DOI:

Endovascular occlusion of right to left arteriovenous shunt associated with persistent left superior vena cava
Kougias, P, Peden, EK, Lin, P, Buergler, J & Lumsden, AB 2006, Journal of Vascular Surgery, vol 44, no. 4, pp. 875-878. DOI:

Echocardiographic features of pseudoaneurysm of the mitral-aortic intervalvular fibrosa
Pirat, B, Buergler, J & Zoghbi, WA 2005, Anadolu Kardiyoloji Dergisi, vol 5, no. 4, pp. 344-345.

Effectiveness of percutaneous intervention for patients with obstructive hypertrophic cardiomyopathy and coronary artery disease
Nambi, V, Buergler, JM, Lakkis, NM, Franklin, J, Spencer, WH & Nagueh, SF 2005, American Journal of Cardiology, vol 96, no. 4, pp. 580-581. DOI:

Effects of SolCD39, a novel inhibitor of platelet aggregation, on platelet deposition and aggregation after PTCA in a porcine model
Buergler, JM, Maliszewski, CR, Broekman, MJ, Kaluza, GL, Schulz, DG, Marcus, AJ, Raizner, AE, Kleiman, NS & Ali, NM 2005, Journal of Thrombosis and Thrombolysis, vol 19, no. 2, pp. 115-122. DOI:

Initial experience with factor-Xa inhibition in percutaneous coronary intervention: The XaNADU-PCI pilot
Alexander, JH, Dyke, CK, Yang, H, Becker, RC, Hasselblad, V, Zillman, LA, Kleiman, NS, Hochman, JS, Berger, PB, Cohen, EA, Lincoff, AM, Saint-Jacques, H, Chetcuti, S, Burton, JR, Buergler, JM, Spence, FP, Shimoto, Y, Robertson, TL, Kunitada, S, Bovill, EG, Armstrong, PW & Harrington, RA 2004, Journal of Thrombosis and Haemostasis, vol 2, no. 2, pp. 234-241. DOI:

Apicoaortic conduit in a patient with severe hemolysis after three aortic valve replacements
Skrabal, CA, Loebe, M, Thompson, LO, Buergler, JM, Youker, KA, Lafuente, JA & Noon, GP 2004, Journal of Thoracic and Cardiovascular Surgery, vol 127, no. 1, pp. 270-272. DOI:

Pharmacodynamic profile of the direct thrombin antagonist bivalirudin given in combination with the glycoprotein IIb/IIIa antagonist eptifibatide
Kleiman, NS, Klem, J, Fernandes, LS, Rubin, H, Challa, S, Solomon, S, Maresh, K, Arora, U, Klem, E, Buergler, J, Mathew, S, Browning, A & DeLao, T 2002, American Heart Journal, vol 143, no. 4, pp. 585-593. DOI:

Long-term effects of intracoronary ß-radiation in balloon- and stent-injured porcine coronary arteries
Kaluza, GL, Raizner, AE, Mazur, W, Schulz, DG, Buergler, JM, Fajardo, LF, Tio, FO & Ali, NM 2001, Circulation, vol 103, no. 16, pp. 2108-2113.