Jerry D. Estep, MD

Associate Professor of Clinical Cardiology, Institute for Academic Medicine
Associate Clinical Member, Research Institute
Program Director, Advanced Heart Failure and Transplant Cardiology Fellowship, Department of Cardiology
Houston Methodist
Weill Cornell Medical College


Dr. Jerry Estep is the Medical Director of the Heart Transplant and LVAD Program at the Methodist DeBakey Heart & Vascular Center and JC Walter Jr. Transplant Center at The Houston Methodist Hospital in Houston, TX. As a staff member he has been actively involved in several multicenter trials including NHLBI (The National Heart, Lung, and Blood Institute) studies for patients with heart failure. His recent original work includes the evaluation of biomarkers and echo indices to facilitate the management and prognostication for patients with decompensated heart failure. Moreover, he is actively involved in research related to multimodality imaging to care for heart failure patients with LVAD’s. He has contributed to several published articles related to advanced heart failure, cardiac transplantation, and advanced treatments for amyloid cardiomyopathy. His recently published manuscripts appear in Circulation, Circulation Heart Failure, JACC, and JACC Imaging. He serves as peer review editor for Circulation, JACC, JASE, Journal of Cardiac Failure and The American Journal Transplantation. He has been recognized for his efforts and contributions and regularly presents at society meetings which include ACC, AHA, ASE, and ISHLT.

Description of Research

Dr. Estep conducts clinical trails of novel therapies and investigational new drugs in patients with decompensated heart failure and mechanical circulatory support/LVADS for heart failure.

Areas Of Expertise

Heart failure Mechanical circulatory support/LVADS for heart failure Investigational new drugs Heart transplant
Education & Training

Residency, University of Texas Southwestern Medical Center
MD, Baylor College of Medicine
Clinical Fellowship, Baylor College of Medicine

Controlled Intrapericardial Delivery Of Prostaglandin Formulations For Heart Failure
Filgueira, CS, Igo, SR, Bruckner, BA, Ferraro, F, Shah, DJ, Estep, JD & Grattoni, A 2017, George and Angelina Kostas Research Center for Cardiovascular Medicine , Houston, United States, 10/24/17 - 10/25/17, .

Risk Stratification of Patients With Current Generation Continuous-Flow Left Ventricular Assist Devices Being Bridged to Heart Transplantation
Guha, A, Nguyen, D, Cruz-Solbes, AS, Amione-Guerra, J, Schutt, RC, Bhimaraj, A, Trachtenberg, BH, Park, MH, Graviss, EA, Gaber, AO, Montane, E, Torre-Amione, G & Estep, JD 2017, ASAIO Journal. DOI: 10.1097/MAT.0000000000000635

Anemia after continuous-flow left ventricular assist device implantation: Characteristics and implications
Amione-Guerra, J, Cruz-Solbes, AS, Bhimaraj, A, Trachtenberg, BH, Pingali, SR, Estep, JD, Park, MH & Guha, A 2017, International Journal of Artificial Organs, vol 40, no. 9, pp. 481-488. DOI: 10.5301/ijao.5000607

Cardiac imaging in patients with heart failure and preserved ejection fraction
Nagueh, SF , Chang, SM , Nabi, F , Shah, DJ & Estep, JD 2017, Circulation: Cardiovascular Imaging, vol 10, no. 9, e006547. DOI: 10.1161/CIRCIMAGING.117.006547

Prevalence of in-hospital nonsteroidal antiinflammatory drug exposure in patients with a primary diagnosis of heart failure
Alvarez, PA, Putney, D, Ogunti, R, Puppala, M, Ganduglia, C, Torre-Amione, G, Schutt, R, Wong, STC & Estep, JD 2017, Cardiovascular Therapeutics, vol 35, no. 3. DOI: 10.1111/1755-5922.12256

Patient-Reported Health-Related Quality of Life Is a Predictor of Outcomes in Ambulatory Heart Failure Patients Treated with Left Ventricular Assist Device Compared with Medical Management: Results from the ROADMAP Study (Risk Assessment and Comparative Effectiveness of Left Ventricular Assist Device and Medical Management)
Stehlik, J, Estep, JD, Selzman, CH, Rogers, JG, Spertus, JA, Shah, KB, Chuang, J, Farrar, DJ & Starling, RC 2017, Circulation: Heart Failure, vol 10, no. 6, e003910. DOI: 10.1161/CIRCHEARTFAILURE.116.003910

PREVENT and hypercoagulable states
Alvarez, P & Estep, JD 2017, Journal of Heart and Lung Transplantation, vol 36, no. 6. DOI: 10.1016/j.healun.2017.01.1296

Accuracy of Seattle Heart Failure Model and HeartMate II Risk Score in Non-Inotrope-Dependent Advanced Heart Failure Patients: Insights from the ROADMAP Study (Risk Assessment and Comparative Effectiveness of Left Ventricular Assist Device and Medical Management in Ambulatory Heart Failure Patients)
Lanfear, DE, Levy, WC, Stehlik, J, Estep, JD, Rogers, JG, Shah, KB, Boyle, AJ, Chuang, J, Farrar, DJ & Starling, RC 2017, Circulation: Heart Failure, vol 10, no. 5, e003745. DOI: 10.1161/CIRCHEARTFAILURE.116.003745

Imaging to Diagnose and Manage Patients in Heart Failure with Reduced Ejection Fraction
Nagueh, SF , Chang, SM , Nabi, F , Shah, DJ & Estep, JD 2017, Circulation: Cardiovascular Imaging, vol 10, no. 4, e005615. DOI: 10.1161/CIRCIMAGING.116.005615

Impact of TPG on Six Month and One Year Waitlist Mortality During Listing for Heart Transplant
Guha, A, Cruz-Solbes, AS, Nguyen, D, Trachtenberg, B, Bhimaraj, A, Graviss, E, Estep, JD & Park, JM 2017, pp. S166-S167. DOI: 10.1016/j.healun.2017.01.437

Extra Corporeal Membrane Oxygenation (ECMO) as a Bridge to Adult Heart Transplantation: Bridge to Bridge Strategy vs Direct ECMO Bridge Strategy (UNOS Analysis)
Hannawi, B, Estep, J, Nguyen, D, Graviss, E, Trachtenberg, B, Bhimaraj, A, Park, JM, Bruckner, BA & Guha, A 2017, pp. S137. DOI: 10.1016/j.healun.2017.01.359

Frontiers in Organ Failure and Transplant Management
Estep, JD & Gaber, AO 2017, Methodist DeBakey cardiovascular journal, vol 12, no. 4 Suppl, pp. 1. DOI: 10.14797/mdcj-12-4s1-1

3D Echocardiography and Ventricular Unloading With Continuous Flow LVAD. Potential Advantages to Optimize Patient Outcome*
Estep, JD 2017, JACC: Cardiovascular Imaging. DOI: 10.1016/j.jcmg.2017.01.022

Caregivers of Patients With Left Ventricular Assist Devices: Possible Impacts on Patients' Mortality and Interagency Registry for Mechanically Assisted Circulatory Support-Defined Morbidity Events
Bruce, CR, Minard, CG, Wilhelms, LA, Abraham, M, Amione-Guerra, J, Pham, L, Grogan, SD, Trachtenberg, B, Smith, ML, Bruckner, BA, Estep, JD & Kostick, KM 2017, Circulation: Cardiovascular Quality and Outcomes, vol 10, no. 1. DOI: 10.1161/CIRCOUTCOMES.116.002879

In-hospital use of non-steroidal anti-inflammatory drugs in patients with heart failure in academic centers in the United States
Alvarez, PA, Nguyen, DT, Schutt, R, Ganduglia, C, Estep, JD, Graviss, EA & Putney, D 2017, International Journal of Risk and Safety in Medicine, vol 28, no. 4, pp. 181-188. DOI: 10.3233/JRS-170736

The Obesity Paradox in End Stage Heart Failure: Does LVAD Resolve the Paradox?
Cruz-Solbes, AS, Nguyen, DT, Trachtenberg, B, Bhimaraj, A, Torre-Amione, G, Graviss, EA, Estep, JD & Guha, A 2017, Journal of Cardiac Failure, vol 23, no. 8, pp. S17. DOI: 10.1016/j.cardfail.2017.07.058

Cannula and Pump Positions Are Associated With Left Ventricular Unloading and Clinical Outcome in Patients With HeartWare Left Ventricular Assist Device
Imamura, T, Adatya, S, Chung, B, Nguyen, A, Rodgers, D, Sayer, G, Sarswat, N, Kim, G, Raikhelkar, J, Ota, T, Song, T, Juricek, C, Medvedofsky, D, Jeevanandam, V, Lang, R, Estep, JD, Burkhoff, D & Uriel, N 2017, Journal of Cardiac Failure. DOI: 10.1016/j.cardfail.2017.09.013

Hemodynamic effects of a fully magnetically levitated centrifugal-flow left ventricular assist device
Estep, JD & Ventura, HO 2017, Journal of Heart and Lung Transplantation, vol 36, no. 1, pp. 19-21. DOI: 10.1016/j.healun.2016.10.017

Impact of age, sex, therapeutic intent, race and severity of advanced heart failure on short-term principal outcomes in the MOMENTUM 3 trial
Goldstein, DJ, Mehra, MR, Naka, Y, Salerno, C, Uriel, N, Dean, D, Itoh, A, Pagani, FD, Skipper, ER, Bhat, G, Raval, N, Bruckner, BA, Estep, JD, Cogswell, R, Milano, C, Fendelander, L, OConnell, JB & Cleveland, J 2017, Journal of Heart and Lung Transplantation. DOI: 10.1016/j.healun.2017.11.001

Left ventricular assist devices versus medical management in ambulatory heart failure patients: An analysis of INTERMACS Profiles 4 and 5 to 7 from the ROADMAP study
Shah, KB, Starling, RC, Rogers, JG, Horstmanshof, DA, Long, JW, Kasirajan, V, Stehlik, J, Chuang, J, Farrar, DJ & Estep, JD 2017, Journal of Heart and Lung Transplantation. DOI: 10.1016/j.healun.2017.12.003