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Jaya Paranilam, PhD

Assistant Research Professor of Biostatistics, Institute for Academic Medicine
Assistant Research Member, Research Institute
Houston Methodist


Dr. Jaya Paranilam is a research associate at the Center for Biostatistics in The Methodist Hospital Research Institute. Prior to joining the institute in 2007, Dr. Paranilam was an epidemiologist for NASA and a research assistant at the University of Texas’ School of Public Health. Dr. Paranilam is a current member of the American Public Health Association.

Description of Research

Design and analysis of clinical trials pertaining to atherosclerosis, hypertension, and renal disease. Other areas of interest include elucidating the determinants of survival and the progression of cognitive impairment in vascular dementia and Alzheimer’s disease.

Areas Of Expertise

Observational research design Statistical methods in epidemiology Analysis of cross-sectional and longitudinal data as well as epidemiological methods of clinical tri
Education & Training

, The University of Texas School of Public Health
, Tulane University

Eighty-six percent failure rate of a modular-neck femoral stem design at 3 to 5 years lessons learned
Bernstein, DT, Meftah, M, Paranilam, J & Incavo, SJ 2016, Journal of Bone and Joint Surgery - American Volume, vol 98, no. 12, pp. e49.

Eighty-six Percent Failure Rate of a Modular-Neck Femoral Stem Design at 3 to 5 Years: Lessons Learned
Bernstein, DT, Meftah, M, Paranilam, J & Incavo, SJ 2016, The Journal of bone and joint surgery. American volume, vol 98, no. 12, pp. e49. DOI:

Cup-to-disc ratio in idiopathic intracranial hypertension without papilloedema
Hamill, E, Kim, JD, Yalamanchili, S, Paranilam, JM, Al Zubidi, N & Lee, AG 2014, Neuro-Ophthalmology, vol 38, no. 2, pp. 69-73. DOI:

Residency education professionalism vignettes
Khan, R, Lee, AG, Golnik, KC & Paranilam, J 2013, Ophthalmology, vol 120, no. 4. DOI:

Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors
Schott, AF, Landis, MD, Dontu, G, Griffith, KA, Layman, RM, Krop, I, Paskett, LA, Wong, H, Dobrolecki, LE, Lewis, MT, Froehlich, AM, Paranilam, J, Hayes, DF, Wicha, MS & Chang, JC 2013, Clinical Cancer Research, vol 19, no. 6, pp. 1512-1524. DOI:

Red cell distribution width is a predictor of mortality in patients undergoing percutaneous coronary intervention
Fatemi, O, Paranilam, J, Rainow, A, Kennedy, K, Choi, J, Cutlip, D, Pencina, M, Berger, PB, Cohen, DJ & Kleiman, NS 2013, Journal of Thrombosis and Thrombolysis, vol 35, no. 1, pp. 57-64. DOI:

Leptin replacement therapy does not improve the abnormal lipid kinetics of hypoleptinemic patients with HIV-associated lipodystrophy syndrome
Sekhar, RV, Jahoor, F, Iyer, D, Guthikonda, A, Paranilam, J, Elhaj, F, Coraza, I & Balasubramanyam, A 2012, Metabolism: Clinical and Experimental, vol 61, no. 10, pp. 1395-1403. DOI:

Differences in risk factors for coronary heart disease among diabetic and nondiabetic individuals from a population with high rates of diabetes: The strong heart study
Xu, J, Lee, ET, Peterson, LE, Devereux, RB, Rhoades, ER, Umans, JG, Best, LG, Howard, WJ, Paranilam, J & Howard, BV 2012, Journal of Clinical Endocrinology and Metabolism, vol 97, no. 10, pp. 3766-3774. DOI:

Genome-wide germline single nucleotide polymorphisms for cancer classification in the Framingham Heart Study
Peterson, L , Paranilam, J , Xu, J & Monzon, F 2010, . in Proceedings of the International Joint Conference on Neural Networks., 5596665, 2010 6th IEEE World Congress on Computational Intelligence, WCCI 2010 - 2010 International Joint Conference on Neural Networks, IJCNN 2010, Barcelona, Spain, 18-23 July. DOI:

Coronary artery calcium scoring in the emergency department: Identifying which patients with chest pain can be safely discharged home
Nabi, F , Chang, SM , Pratt, CM , Paranilam, J , Peterson, LE, Frias, ME & Mahmarian, JJ 2010, Annals of Emergency Medicine, vol 56, no. 3, pp. 220-229. DOI: