Donna Coffey, MD

Assistant Professor of Clinical Pathology and Genomic Medicine, Institute for Academic Medicine
Houston Methodist
Weill Cornell Medical College


Dr. Coffey received her MD degree from the University of Costa Rica in San Jose in 1991. She then completed a pathology residency and cytopathology fellowship at the Baylor College of Medicine in Houston, Texas, before joining the faculty at Baylor as an assistant professor in the Department of Pathology. She joined Houston Methodist in 2005 and received her Weill Cornell Faculty appointment in 2008.

Description of Research

Dr. Coffey is a general surgical pathologist with subspecialty training in cytopathology. Her areas of interest are gynecologic pathology and cytopathology. She is currently involved in several collaborative studies using tissue microarrays of gynecologic malignancies.

Education & Training

, Baylor College of Medicine
, Ciudad Universitaria

Pathologic Staging of Endometrial Cancers: Is there Benefit to Submitting Adipose Tissue Remaining after Gross Identification of Lymph Nodes?
Okoye, EI , Coffey, D & Deavers, M 2016, United States and Canadian Academy of Pathology 2016 Annual Meeting, Seattle, 3/14/16 - 3/18/16, .

Rapid On Site Evaluation (ROSE) in Uveal Melanomas for Diagnostic Adequacy and Optimal Triaging for Molecular Gene Expression Profile (GEP) Testing: A Series Analysis of 67 Cases
Coffey, D & Chevez-Barrios, P 2016, American Society of Cytopathology 2016 Annual Meeting, 11/4/16 - 11/6/16, pp. S45-S46.

The Utility of Core Needle Biopsy and Fine-Needle Aspiration in the Workup of Tumors of Suspected Müllerian Origin
Crumley, S, Okoye, E, Deavers, M & Coffey, D 2015, Acta Cytologica, vol 59, no. 6, pp. 465-473. DOI:

The ovary is an alternative site of origin for high-grade serous ovarian cancer in mice
Kim, J, Coffey, DM, Ma, L & Matzuk, MM 2015, Endocrinology, vol 156, no. 6, pp. 1975-1981. DOI:

In reply
Wright, AM, Mody, D & Coffey, DM 2014, Archives of Pathology and Laboratory Medicine, vol 138, no. 3, pp. 300-301. DOI:

Genotype-specific prevalence and distribution of human papillomavirus genotypes in underserved Latino women with abnormal Papanicolaou tests
Zhou, H, Mody, DR, Schwartz, MR, Coffey, DM, Smith, D, Zwain, OA, Kamarapu, NP, Brown, JB, Medina, M, Hodgson, SR, Hobday, CD & Ge, Y 2014, Journal of the American Society of Cytopathology, vol 3, no. 1, pp. 42-48. DOI:

PAX2 and PAX8: Useful markers for metastatic effusions
Waters, L, Crumley, S, Truong, L, Mody, D & Coffey, D 2014, Acta Cytologica, vol 58, no. 1, pp. 60-66. DOI:

Tumor-to-tumor metastasis with Endometrial carcinoma metastatic to squamous cell carcinoma of vulva: The first reported case
Wimmer, JL, Coffey, DM, Kaplan, AL, Ayala, AG & Ro, JY 2013, Archives of Pathology and Laboratory Medicine, vol 137, no. 12, pp. 1825-1828. DOI:

Expression and functional pathway analysis of nuclear receptor NR2F2 in ovarian cancer
Hawkins, SM, Loomans, HA, Wan, YW, Ghosh-Choudhury, T, Coffey, D, Xiao, W, Liu, Z, Sangi-Haghpeykar, H & Anderson, ML 2013, Journal of Clinical Endocrinology and Metabolism, vol 98, no. 7. DOI:

Digital slide imaging in cervicovaginal cytology: A pilot study
Wright, AM, Smith, D, Dhurandhar, B, Fairley, T, Scheiber-Pacht, M, Chakraborty, S, Gorman, BK, Mody, D & Coffey, DM 2013, Archives of Pathology and Laboratory Medicine, vol 137, no. 5, pp. 618-624. DOI:

Should LSIL-H be a distinct cytology category? A study on the frequency and distribution of 40 human papillomavirus genotypes in 808 Women
Zhou, H, Schwartz, MR, Coffey, D, Smith, D, Mody, DR & Ge, Y 2012, Cancer Cytopathology, vol 120, no. 6, pp. 373-379. DOI:

High-grade serous ovarian cancer arises from fallopian tube in a mouse model
Kim, J, Coffey, DM, Creighton, CJ, Yu, Z, Hawkins, SM & Matzuk, MM 2012, Proceedings of the National Academy of Sciences of the United States of America, vol 109, no. 10, pp. 3921-3926. DOI:

Identification of tissue of origin in body fluid specimens using a gene expression microarray assay
Stance, GA, Coffey, D, Alvarez, K, Halks-Miller, M, Lal, A, Mody, D, Koen, T, Fairley, T & Monzon, FA 2012, Cancer Cytopathology, vol 120, no. 1, pp. 62-70. DOI:

PAX2 and PAX8 expression in primary and metastatic müllerian epithelial tumors: A comprehensive comparison
Ozcan, A, Liles, N, Coffey, D, Shen, SS & Truong, LD 2011, American Journal of Surgical Pathology, vol 35, no. 12, pp. 1837-1847. DOI:

Clinicopathologic and immunohistochemical characteristics of adult primary cardiac angiosarcomas: Analysis of 10 cases
Ge, Y , Ro, JY, Kim, D, Kim, CH, Reardon, MJ, Blackmon, S, Zhai, J, Coffey, D, Benjamin, RS & Ayala, AG 2011, Annals of Diagnostic Pathology, vol 15, no. 4, pp. 262-267. DOI:

PAX 8 expression in non-neoplastic tissues, primary tumors, and metastatic tumors: A comprehensive immunohistochemical study
Ozcan, A, Shen, SS, Hamilton, C, Anjana, K, Coffey, D, Krishnan, B & Truong, LD 2011, Modern Pathology, vol 24, no. 6, pp. 751-764. DOI:

Clinical and biological impact of EphA2 overexpression and angiogenesis in endometrial cancer
Merritt, WM, Kamat, AA, Hwang, JY, Bottsford-Miller, J, Lu, C, Lin, YG, Coffey, D, Spannuth, W, Nugent, E, Han, LY, Landen, CN, Nick, AM, Stone, RL, Coffman, KT, Bruckheimer, E, Broaddus, R, Gershenson, DM, Coleman, RL & Sood, AK 2010, Cancer Biology and Therapy, vol 10, no. 12, pp. 1306-1314. DOI:

PAX-2 is a helpful marker for diagnosing metastatic renal cell carcinoma: Comparison with the renal cell carcinoma marker antigen and kidney-specific cadherin
Ozcan, A, Zhai, Q, Javed, R, Shen, SS, Coffey, D, Krishnan, B & Truong, LD 2010, Archives of Pathology and Laboratory Medicine, vol 134, no. 8, pp. 1121-1129.

PAX-2 expression in non-neoplastic, primary neoplastic, and metastatic neoplastic tissue: A comprehensive immunohistochemical study
Zhai, QJ, Ozcan, A, Hamilton, C, Shen, SS, Coffey, D, Krishnan, B & Truong, LD 2010, Applied Immunohistochemistry and Molecular Morphology, vol 18, no. 4, pp. 323-332. DOI:

EphA2 overexpression is associated with lack of hormone receptor expression and poor outcome in endometrial cancer
Kamat, AA , Coffey, D, Merritt, WM, Nugent, E, Urbauer, D, Lin, YG, Edwards, C, Broaddus, R, Coleman, RL & Sood, AK 2009, Cancer, vol 115, no. 12, pp. 2684-2692. DOI: