Constance M. Mobley VIEW CLINICAL PROFILE

Constance M. Mobley, MD, PhD, FACS

Associate Professor of Clinical Surgery, Academic Institute
Associate Clinical Member , Research Institute
Associate Director of Liver Transplantation, J.C. Walter Jr. Transplant Center
Houston Methodist
Weill Cornell Medical College


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Biography

Dr. Constance M. Mobley earned her MD and PhD from Vanderbilt University School of Medicine in 2003. She completed her General Surgery residency and fellowship in Surgical Critical Care at the University of Michigan. Subsequently, she went on to complete a fellowship in Abdominal Multi-Organ Transplant and Hepatobiliary Surgery at UCLA David Geffen School of Medicine. In 2014, Dr. Mobley joined the staff of Houston Methodist Hospital in Houston, TX and is an Assistant Professor of Surgery at Weill Cornell Medical College.

Dr. Mobley is a board-certified surgeon in surgical critical care, and transplant surgery. She is currently the Medical Director of the Surgical & Liver ICU and Program Director for the Surgical Critical Care Fellowship. She serves as an active member on several hospital committees and professional societies and is a current member of the Legislative and Regulatory Committee.

 

Description of Research

Dr. Mobley’s areas of special interests include management of the critically ill liver failure patient, methodology to improve liver transplant success in high MELD patients, and management of cirrhotic cardiomyopathy and post-transplant cardiomyopathy. She is actively involved in several clinical research trials spanning transplant immunology, liver disease, and support devices to both prolong donor organ utility, and bridge to liver transplant.

Areas Of Expertise

Liver Disease Transplant immunology
Publications

Effect of a Hispanic outreach program on referral and liver transplantation volume at a single center
Kodali, S, Mobley, CM, Brombosz, EW, Lopez, A, Graves, R, Ontiveros, J, Velazquez, M, Saharia, A, Cheah, YL, Simon, CJ, Valverde, C, Brown, A, Corkrean, J, Moore, LW, Graviss, EA, Victor, DW, Maresh, K, Hobeika, MJ, Egwim, C & Ghobrial, RM 2024, , Transplant Immunology, vol. 84, 102034. https://doi.org/10.1016/j.trim.2024.102034

Single-center Outcomes After Liver Transplantation With SARS-CoV-2–Positive Donors: An Argument for Increased Utilization
Connor, AA, Adelman, MW, Mobley, CM, Moaddab, M, Erhardt, AJ, Hsu, DE, Brombosz, EW, Sanghvi, M, Lee Cheah, Y, Simon, CJ, Hobeika, MJ, Saharia, AS, Victor, DW, Kodali, S, Basra, T, Graviss, EA, Nguyen, DT, Elsaiey, A, Moore, LW, Nigo, M, Drews, AL, Grimes, KA, Arias, CA, Li, XC, Gaber, AO & Ghobrial, RM 2024, , Transplantation Direct, vol. 10, no. 4, pp. E1590. https://doi.org/10.1097/TXD.0000000000001590

Bloodstream infections after solid organ transplantation: clinical epidemiology and antimicrobial resistance (2016–21)
Adelman, MW, Connor, AA, Hsu, E, Saharia, A, Mobley, CM, Victor, DW, Hobeika, MJ, Lin, J, Grimes, KA, Ramos, E, Pedroza, C, Brombosz, EW, Ghobrial, RM & Arias, CA 2024, , JAC-Antimicrobial Resistance, vol. 6, no. 1, 158, pp. dlad158. https://doi.org/10.1093/jacamr/dlad158

Summary of a consensus conference on heart-liver transplantation
Consensus Conference participants 2023, , American Journal of Transplantation, vol. 24, no. 3, pp. 380-390. https://doi.org/10.1016/j.ajt.2023.12.002

Modern Outcomes After Liver Retransplantation: A Single-center Experience
Connor, AA, Saharia, A, Mobley, CM, Hobeika, MJ, Victor, DW, Kodali, S, Brombosz, EW, Graviss, EA, Nguyen, DT, Moore, LW, Gaber, AO & Ghobrial, RM 2023, , Transplantation, vol. 107, no. 7, pp. 1513-1523. https://doi.org/10.1097/TP.0000000000004500

Development and validation of a REcurrent Liver cAncer Prediction ScorE (RELAPSE) following liver transplantation in patients with hepatocellular carcinoma: Analysis of the US Multicenter HCC Transplant Consortium
Tran, BV, Moris, D, Markovic, D, Zaribafzadeh, H, Henao, R, Lai, Q, Florman, SS, Tabrizian, P, Haydel, B, Ruiz, RM, Klintmalm, GB, Lee, DD, Taner, CB, Hoteit, M, Levine, MH, Cillo, U, Vitale, A, Verna, EC, Halazun, KJ, Tevar, AD, Humar, A, Chapman, WC, Vachharajani, N, Aucejo, F, Lerut, J, Ciccarelli, O, Nguyen, MH, Melcher, ML, Viveiros, A, Schaefer, B, Hoppe-Lotichius, M, Mittler, J, Nydam, TL, Markmann, JF, Rossi, M, Mobley, C, Ghobrial, M, Langnas, AN, Carney, CA, Berumen, J, Schnickel, GT, Sudan, DL, Hong, JC, Rana, A, Jones, CM, Fishbein, TM, Busuttil, RW, Barbas, AS & Agopian, VG 2023, , Liver Transplantation, vol. 29, no. 7, pp. 683-697. https://doi.org/10.1097/LVT.0000000000000145

Factors affecting survival after liver retransplantation: a systematic review and meta-analysis
Brombosz, EW, Moore, LW, Mobley, CM, Kodali, S, Saharia, A, Hobeika, MJ, Connor, AA, Victor, III, DW, Cheah, YL, Simon, CJ, Gaber, AO & Ghobrial, RM 2023, , Frontiers in Transplantation, vol. 2, pp. 1181770. https://doi.org/10.3389/frtra.2023.1181770

Progress in Combined Liver-lung Transplantation at a Single Center
Connor, AA, Huang, HJ, Mobley, CM, Graviss, EA, Nguyen, DT, Goodarzi, A, Saharia, A, Yau, S, Hobeika, MJ, Suarez, EE, Moaddab, M, Brombosz, EW, Moore, LW, Yi, SG, Gaber, AO & Ghobrial, RM 2023, , Transplantation Direct, vol. 9, no. 5, pp. E1482. https://doi.org/10.1097/TXD.0000000000001482

Outcomes in liver transplant recipients with nonalcoholic fatty liver disease-related HCC: results from the US multicenter HCC transplant consortium
US Multicenter HCC Transplant Consortium 2023, , Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, vol. 29, no. 1, pp. 34-47. https://doi.org/10.1097/LVT.0000000000000007

Graft and Patient Survival after Liver Transplantation
Yi, S, Mobley, CM & Ghobrial, RM 2022, . in P Burra (ed.), Textbook of Liver Transplantation. Springer, pp. 433-448.

Perioperative cangrelor in patients with recent percutaneous coronary intervention undergoing liver transplantation: A case series
Succar, L, Lopez, CN, Victor, DW, Lindberg, SA, Saharia, A, Sheth, S & Mobley, CM 2022, , Pharmacotherapy, vol. 42, no. 3, pp. 263-267. https://doi.org/10.1002/phar.2661

Perioperative cangrelor in patients with recent percutaneous coronary intervention undergoing liver transplantation: A case series
Succar, L, Lopez, CN, Victor, DW, Lindberg, SA, Saharia, A, Sheth, S & Mobley, CM 2022, , Pharmacotherapy, vol. 42, no. 3, pp. 263-267. https://doi.org/10.1002/phar.2661

Risk Factors Associated with an Impaired Antibody Response in Kidney Transplant Recipients following 2 Doses of the SARS-CoV-2 mRNA Vaccine
Yi, SG, Moore, LW, Eagar, T, Graviss, EA, Nguyen, DT, Ibrahim, H, Huang, HJ, Hobeika, M, McMillan, R, Saharia, A, Mobley, C, Podder, H, Drews, A, Ghobrial, RM, Gaber, AO & Knight, RJ 2022, , Transplantation Direct, vol. 8, no. 1, e1257, pp. e1257. https://doi.org/10.1097/TXD.0000000000001257, https://doi.org/10.1097/TXD.0000000000001257

Early humoral immune response to two doses of severe acute respiratory syndrome coronavirus 2 vaccine in a diverse group of solid organ transplant candidates and recipients
Huang, HJ, Yi, SG, Mobley, CM, Saharia, A, Bhimaraj, A, Moore, LW, Kloc, M, Adrogue, HE, Graviss, EA, Nguyen, DT, Eagar, TN, Jones, SL, Ankoma-Sey, V, MacGillivray, TE, Knight, RJ, Gaber, AO & Ghobrial, RM 2022, , Clinical Transplantation, vol. 36, no. 5, e14600. https://doi.org/10.1111/ctr.14600, https://doi.org/10.1111/ctr.14600

Early humoral immune response to two doses of severe acute respiratory syndrome coronavirus 2 vaccine in a diverse group of solid organ transplant candidates and recipients
Huang, HJ, Yi, SG, Mobley, CM, Saharia, A, Bhimaraj, A, Moore, LW, Kloc, M, Adrogue, HE, Graviss, EA, Nguyen, DT, Eagar, TN, Jones, SL, Ankoma-Sey, V, MacGillivray, TE, Knight, RJ, Gaber, AO & Ghobrial, RM 2022, , Clinical Transplantation, vol. 36, no. 5, e14600. https://doi.org/10.1111/ctr.14600

Combined liver transplantation and sleeve gastrectomy: Report of a brief-interval staged approach
Tariq, N, Saharia, A, Nwokedi, U, Hobeika, MJ, Mobley, CM, Hsu, D, Potter, LM, Moore, LW, Elaileh, A, Sherman, V & Ghobrial, RM 2023, , Liver Transplantation, vol. 29, no. 4, pp. 422-430. https://doi.org/10.1002/lt.26560

Combined liver transplantation and sleeve gastrectomy: Report of a brief-interval staged approach
Tariq, N, Saharia, A, Nwokedi, U, Hobeika, MJ, Mobley, CM, Hsu, D, Potter, LM, Moore, LW, Elaileh, A, Sherman, V & Ghobrial, RM 2023, , Liver Transplantation, vol. 29, no. 4, pp. 422-430. https://doi.org/10.1002/lt.26560

Graft and Patient Survival after Liver Transplantation
Yi, SG, Mobley, C & Ghobrial, RM 2022, . in Textbook of Liver Transplantation: A Multidisciplinary Approach. Springer International Publishing, pp. 421-432. https://doi.org/10.1007/978-3-030-82930-8_25

Pre-transplant T-cell Clonality: An Observational Study of a Biomarker for Prediction of Sepsis in Liver Transplant Recipients
Jones, SL, Moore, LW, Li, XC, Mobley, CM, Fields, PA, Graviss, EA, Nguyen, DT, Nolte Fong, J, Saharia, A, Hobeika, MJ, McMillan, RR, Victor, DW, Minze, LJ, Gaber, AO & Ghobrial, RM 2021, , Annals of surgery, vol. 274, no. 3, pp. 411-418. https://doi.org/10.1097/SLA.0000000000004998

Re: Delayed Implantation of Pumped Kidneys Decreases Renal Allograft Futility in Combined Liver-Kidney Transplantation
Lunsford, KE, Agopian, VG, Yi, SG, Nguyen, DTM, Graviss, EA, Harlander-Locke, MP, Saharia, A, Kaldas, FM, Mobley, CM, Zarrinpar, A, Hobeika, MJ, Veale, JL, Podder, H, Farmer, DG, Knight, RJ, Danovitch, GM, Gritsch, HA, Li, XC, Ghobrial, RM, Busuttil, RW & Gaber, AO 2021, , Journal of Urology, vol. 205, no. 4, pp. 1215. https://doi.org/10.1097/JU.0000000000001610

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