Bin S. Teh, MD

Professor of Radiation Oncology, Institute for Academic Medicine
Full Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Biography

Dr. Teh is a professor and vice chair of the Department of Radiation Oncology at Houston Methodist Hospital and Weill Medical School of Cornell. Dr. Teh has contributed significantly to the field of radiation oncology – encompassing radiotherapy technology, radiation physics, molecular radiobiology and the translation of advances in these areas to clinical use. He has been instrumental in pioneering new technology in radiation oncology including APBI (accelerated partial breast irradiation), IMRT (intensity-modulated radiation therapy), IGRT (image-guided radiation therapy), SBRT (stereotactic body radiation therapy), SRS (stereotactic radiosurgery), brachytherapy as well as combined radiotherapy and gene therapy. Dr. Teh treated the first breast cancer patient in Houston with multi-lumen catheter (Contura) high dose rate brachytherapy for partial breast irradiation. This is a short course of five days irradiation, as compared to the conventional six weeks irradiation for breast cancer. Partial breast irradiation is a novel approach to spare more normal tissues.

Dr. Teh earned his medical degree from the University of Queensland in Queensland, Australia. He completed his Radiation Oncology residency, training and fellowship in IMRT at the Baylor College of Medicine in Houston, Texas. Dr. Teh is active in ASTRO (American Society of Therapeutic Radiology and Oncology), RSNA (Radiological Society of North America and ARS (American Radium Society). He is the principal investigator for RTOG (Radiation Therapy Oncology Group) at Houston Methodist Hospital. Dr. Teh has published more than 100 peer-reviewed articles on topics such as IMRT for breast cancer, editorials, 15 book chapters and a textbook on PET-CT in radiotherapy. He plays an important role in breast cancer patient care, clinical research and the education of residents and students.

Description of Research

Dr. Teh’s research focuses on the treatment of genito-urinary malignancies and unlocking the myth of radio-resistance in cancers especially renal cell carcinoma. Other research interests include Intensity modulated radiation therapy (IMRT) for prostate cancer, head and neck cancer, central nervous system tumor, pediatric cancer and breast cancer, stereotactic radiosurgery (SRS), stereotactic body radiotherapy (SBRT), stereotactic radiation therapy (SRT) and image-guided radiation therapy (IGRT), brachytherapy for prostate cancer, breast cancer and endobronchial tumors, SRS and SBRT for primary and metastatic renal cell carcinoma as well as hepatocellular carcinoma, the role of combined radiotherapy and gene therapy for cancers including prostate cancer, renal cell carcinoma, bladder cancer, pancreatic cancer, glioblastoma multiforme, cervical cancer and head and neck cancer, combining targeted therapy (AKT-inhibitor, mTOR inhibitor, tyrosine kinase inhibitor) with radiotherapy for cancer treatment, and combining oncolytic virus with radiotherapy in overcoming radio-resistant tumors in oncology.

Areas Of Expertise

Cancer stem cells Radio-resistance Prostate Movement study Post-prostatectomy IMRT Gene expression profiling in cancer Proteomics in oncology
Education & Training

Clinical Fellowship , Baylor College of Medicine
Residency , Baylor College of Medicine
MD , University of Queensland
Publications

Radiation therapy utilization and outcomes for older women with breast cancer: Impact of molecular subtype and tumor grade
Haque, W, Kee Yuan, DM, Verma, V, Butler, EB, Teh, BS, Wiederhold, L & Hatch, S 2017, Breast, vol 35, pp. 34-41. DOI:

The utility of positron emission tomography/computed tomography in target delineation for stereotactic body radiotherapy for liver metastasis from primary gastric cancer: An illustrative case report and literature review
Lewis, GD, Chiang, SB, Butler, EB & Teh, BS 2017, Journal of Gastrointestinal Oncology, vol 8, no. 3, pp. E39-E42. DOI:

Patterns of care and outcomes of multi-agent versus single-agent chemotherapy as part of multimodal management of low grade glioma
Haque, W, Verma, V, Butler, EB & Teh, BS 2017, Journal of Neuro-Oncology. DOI:

Consensus guidelines for postoperative stereotactic body radiation therapy for spinal metastases: results of an international survey
Redmond, KJ, Lo, SS, Soltys, SG, Yamada, Y, Barani, IJ, Brown, PD, Chang, EL, Gerszten, PC, Chao, ST, Amdur, RJ, De Salles, AAF, Guckenberger, M, Teh, BS, Sheehan, J, Kersh, CR, Fehlings, MG, Sohn, MJ, Chang, UK, Ryu, S, Gibbs, IC & Sahgal, A 2017, Journal of neurosurgery. Spine, vol 26, no. 3, pp. 299-306. DOI:

Trends in the use of implantable accelerated partial breast irradiation for ductal carcinoma in situ: Implications of the recent amendments to the American Society for Radiation Oncology consensus guidelines
Haque, W, Verma, V, Haque, A, Butler, EB & Teh, BS 2017, Brachytherapy, vol 16, no. 2, pp. 402-408. DOI:

Histopathologic Analysis of Transvitreal Fine Needle Aspiration Biopsy Needle Tracts for Uveal Melanoma
Kim, RS, Chevez-Barrios, P, Bretana, ME, Wong, TP, Teh, BS & Schefler, AC 2017, American Journal of Ophthalmology, vol 174, pp. 9-16. DOI:

Early outcomes of uveal melanoma treated with intraoperative ultrasound guided brachytherapy using custom built plaques
Tann, AW, Teh, BS, Scarboro, SB, Lewis, GD, Bretana, ME, Croft, PC, Raizen, Y, Butler, EB, Kim, RS, Chevez-Barrios, P & Schefler, AC 2017, Practical Radiation Oncology. DOI:

Trends in cardiac mortality in women with ductal carcinoma in situ
Haque, W, Verma, V, Haque, A, Butler, EB & Teh, BS 2017, Breast Cancer Research and Treatment, vol 161, no. 2, pp. 345-351. DOI:

Prognostic Factors, Treatment, and Outcomes in Early Stage, Invasive Papillary Breast Cancer: A SEER Investigation of Less Aggressive Treatment in a Favorable Histology
Fakhreddine, MH, Haque, W, Ahmed, A, Schwartz, MR, Farach, AM, Paulino, AC, Bonefas, E, Miltenburg, D, Niravath, P, Butler, BB & Teh, BS 2016, American Journal of Clinical Oncology: Cancer Clinical Trials. DOI:

Addition of chemotherapy to definitive radiotherapy for IB1 and IIA1 cervical cancer: Analysis of the National Cancer Data Base
Haque, W, Verma, V, Fakhreddine, M, Hatch, S, Butler, EB & Teh, BS 2016, Gynecologic Oncology. DOI:

Phase II multicenter study of gene-mediated cytotoxic immunotherapy as adjuvant to surgical resection for newly diagnosed malignant glioma
Wheeler, LA, Manzanera, AG, Bell, SD, Cavaliere, R, McGregor, JM, Grecula, JC, Newton, HB, Lo, SS, Badie, B, Portnow, J, Teh, BS, Trask, TW, Baskin, DS, New, PZ, Aguilar, LK, Aguilar-Cordova, E & Chiocca, EA 2016, Neuro-Oncology, vol 18, no. 8, pp. 1137-1145. DOI:

Chemotherapy in non-small cell lung cancer: opportunities for advancement
Akhtari, M, Bernicker, EH & Teh, BS 2016, Chinese Journal of Lung Cancer, vol 35, no. 1, pp. 56. DOI:

Stereotactic body radiotherapy for pancreatic cancer: recent progress and future directions
Myrehaug, S, Sahgal, A, Russo, SM, Lo, SS, Rosati, LM, Mayr, NA, Lock, M, Small, W, Dorth, JA, Ellis, RJ, Teh, BS & Herman, JM 2016, Expert Review of Anticancer Therapy, pp. 1-8. DOI:

Changes in treatment patterns and impact of radiotherapy for early stage diffuse large B cell lymphoma after Rituximab: A population-based analysis
Haque, W, Dabaja, B, Tann, A, Khan, M, Szeja, S, Butler, EB & Teh, BS 2016, Radiotherapy and Oncology. DOI:

Accelerated partial breast irradiation: Advances and controversies
Akhtari, M & Teh, BS 2016, Ai zheng = Aizheng = Chinese journal of cancer, vol 35, no. 4. DOI:

Next-generation sequencing of a cohort of pulmonary large cell carcinomas reclassified by world health organization 2015 criteria
Driver, BR, Portier, BP, Mody, DR, Deavers, M, Bernicker, EH, Kim, MP, Teh, BS, Santacruz, JF, Kopas, L, Munden, RF & Cagle, PT 2016, Archives of Pathology and Laboratory Medicine, vol 140, no. 4, pp. 312-317. DOI:

Technical know-how in stereotactic ablative radiotherapy (SABR)
Lo, SS, Foote, M, Siva, S, Slotman, BJ, Teh, BS, Guckenberger, M, Tan, D, Mayr, NA & Sahgal, A 2016, Journal of Medical Radiation Sciences, vol 63, no. 1, pp. 5-8. DOI:

Consensus statement from the International Radiosurgery Oncology Consortium for Kidney for primary renal cell carcinoma
Siva, S, Ellis, RJ, Ponsky, L, Teh, BS, Mahadevan, A, Muacevic, A, Staehler, M, Onishi, H, Wersall, P, Nomiya, T & Lo, SS 2016, Future Oncology, vol 12, no. 5, pp. 637-645. DOI:

Clinical outcomes, toxicity, and cosmesis in breast cancer patients with close skin spacing treated with accelerated partial breast irradiation (APBI) using multi-lumen/catheter applicators
Akhtari, M, Abboud, M, Szeja, S, Pino, R, Lewis, GD, Bass, BL, Miltenburg, DM, Butler, EB & Teh, BS 2016, Journal of Contemporary Brachytherapy, vol 8, no. 6, pp. 497-504. DOI:

Estimating lung respiratory motion using combined global and local statistical models
Xue, Z, Pino, R & Teh, B 2016, . in Patch-Based Techniques in Medical Imaging - 2nd International Workshop, Patch-MI 2016 held in conjunction with MICCAI 2016, Proceedings. vol. 9993 LNCS, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 9993 LNCS, Springer Verlag, pp. 133-140, 2nd International Workshop on Patch-Based Techniques in Medical Imaging, Patch-MI 2016 held in conjunction with 19th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2016, Athens, Greece, 17-17 October. DOI: