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Arturas Ziemys,

Houston Methodist


Areas Of Expertise

Diffusion Drug development Nanofluidics Particulate materials Model systems
Publications

Computational analysis of drug transport in tumor microenvironment as a critical compartment for nanotherapeutic pharmacokinetics
Ziemys, A, Klemm, S, Milosevic, M, Yokoi, K, Ferrari, M & Kojic, M 2016, Drug Delivery, vol 23, no. 7, pp. 2524-2531. DOI:

The protein kinase promiscuities in the cancer-preventive mechanisms of NSAIDs
Norvaisas, P, Chan, D, Yokoi, K, Dave, B & Ziemys, A 2016, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), vol 25, no. 1, pp. 77-84. DOI:

The protein kinase promiscuities in the cancer-preventive mechanisms of NSAIDs
Norvaisas, P, Chan, D, Yokoi, K, Dave, B & Ziemys, A 2016, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), vol 25, no. 1, pp. 77-84.

Reduced cationic nanoparticle cytotoxicity based on serum masking of surface potential
McConnell, KI, Shamsudeen, S, Meraz, IM, Mahadevan, TS, Ziemys, A, Rees, P, Summers, HD & Serda, RE 2016, Journal of Biomedical Nanotechnology, vol 12, no. 1, pp. 154-164. DOI:

Computational models for convective and diffusive drug transport in capillaries and tissue
Kojic, M, Milosevic, M, Isailovic, V, Simic, V, Ferrari, M & Ziemys, A 2015, . in 2015 IEEE 15th International Conference on Bioinformatics and Bioengineering, BIBE 2015., 7367633, Institute of Electrical and Electronics Engineers Inc. 15th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2015, Belgrade, Serbia, 2-4 November. DOI:

Liposomal doxorubicin extravasation controlled by phenotype-specific transport properties of tumor microenvironment and vascular barrier
Yokoi, K, Chan, D, Kojic, M, Milosevic, M, Engler, D, Matsunami, R, Tanei, T, Saito, Y, Ferrari, M & Ziemys, A 2015, Journal of Controlled Release, vol 217, pp. 293-299. DOI:

Capillary collagen as the physical transport barrier in drug delivery to tumor microenvironment
Ziemys, A , Yokoi, K & Kojic, M 2015, Tissue barriers, vol 3, no. 3, pp. e1037418. DOI:

Physicochemical properties affect the synthesis, controlled delivery, degradation and pharmacokinetics of inorganic nanoporous materials
Yazdi, IK, Ziemys, A, Evangelopoulos, M, Martinez, JO, Kojic, M & Tasciotti, E 2015, Nanomedicine, vol 10, no. 19, pp. 3057-3075. DOI:

A multi-scale FE model for convective-diffusive drug transport within tumor and large vascular networks
Kojic, M, Milosevic, M, Kojic, N, Starosolski, Z, Ghaghada, K, Serda, R, Annapragada, A, Ferrari, M & Ziemys, A 2015, Computer Methods in Applied Mechanics and Engineering, vol 294, pp. 100-122. DOI:

Mass partitioning effects in diffusion transport
Kojic, M, Milosevic, M, Wu, S, Blanco, E, Ferrari, M & Ziemys, A 2015, Physical Chemistry Chemical Physics, vol 17, no. 32, pp. 20630-20635. DOI:

Coupling fluid and solid domains in modeling drug transport within tumor
Kojic, M, Milosevic, M, Simic, V, Ziemys, A & Ferrari, M 2015, . in COUPLED PROBLEMS 2015 - Proceedings of the 6th International Conference on Coupled Problems in Science and Engineering. International Center for Numerical Methods in Engineering, pp. 583-592, 6th International Conference on Computational Methods for Coupled Problems in Science and Engineering, COUPLED PROBLEMS 2015, Venice, Italy, 18-20 May.

Delivering Enhanced Testosterone Replacement Therapy through Nanochannels
Ferrati, S, Nicolov, E, Bansal, S, Zabre, E, Geninatti, T, Ziemys, A, Hudson, L, Ferrari, M, Goodall, R, Khera, M, Palapattu, G & Grattoni, A 2015, Advanced Healthcare Materials, vol 4, no. 3, pp. 446-451. DOI:

Computational analysis of drug transport in tumor microenvironment as a critical compartment for nanotherapeutic pharmacokinetics
Ziemys, A, Klemm, S, Milosevic, M, Yokoi, K, Ferrari, M & Kojic, M 2015, Drug Delivery, vol 23, no. 7, pp. 2524-2531. DOI:

Sustained administration of hormones exploiting nanoconfined diffusion through nanochannel membranes
Geninatti, T, Lyle Hood, R, Bruno, G, Jain, P, Nicolov, E, Ziemys, A & Grattoni, A 2015, Materials, vol 8, no. 8, pp. 5276-5288. DOI:

Capillary-wall collagen as a biophysical marker of nanotherapeutic permeability into the tumor microenvironment
Yokoi, K , Kojic, M, Milosevic, M, Tanei, T, Ferrari, M & Ziemys, A 2014, Cancer Research, vol 74, no. 16, pp. 4239-4246. DOI:

Polymer nanoparticles encased in a cyclodextrin complex shell for potential site- and sequence-specific drug release
Ruiz-Esparza, GU, Wu, S, Segura-Ibarra, V, Cara, FE, Evans, KW, Milosevic, M, Ziemys, A, Kojic, M, Meric-Bernstam, F, Ferrari, M & Blanco, E 2014, Advanced Functional Materials, vol 24, no. 30, pp. 4753-4761. DOI:

A multiscale MD-FE model of diffusion in composite media with internal surface interaction based on numerical homogenization procedure
Kojic, M, Milosevic, M, Kojic, N, Kim, K, Ferrari, M & Ziemys, A 2014, Computer Methods in Applied Mechanics and Engineering, vol 269, pp. 123-138. DOI:

A computational study of trajectories of micro- and nano-particles with different shapes in flow through small channels
Isailovic, V, Kojic, M, Milosevic, M, Filipovic, N, Kojic, N, Ziemys, A & Ferrari, M 2014, Journal of the Serbian Society for Computational Mechanics, vol 8, no. 2, pp. 14-28.

Transport in nanoconfinement and within blood vessel wall
Ziemys, A, Filipovic, N, Ferrari, M & Kojic, M 2014, . in Computational Surgery and Dual Training: Computing, Robotics and Imaging. Springer New York, pp. 273-288. DOI:

The role of payload hydrophobicity in nanotherapeutic pharmacokinetics
Norvaisas, P & Ziemys, A 2014, Journal of Pharmaceutical Sciences, vol 103, no. 7, pp. 2147-2156. DOI: