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Anna Tampieri, PhD

Full Affiliate Member, Research Institute
Houston Methodist


Dr. Tampieri's research focus is materials science with special attention to inorganic chemistry applications in ceramic materials and bio-hybrid composites. Early in her career from 1986 to 1995, Dr. Tampieri coordinated research collaborations for the development of High-Tc Ceramic Superconductors.

Beginning in 1995, Dr. Tampieri created a new research group dedicated to the development of biomaterials and biotechnology for regenerative medicine. Her research team combines a high degree of technical specialization with broad interdisciplinary expertise that supports a large number of national and international research projects.

Dr. Tampieri's research is internationally recognized for contributions to global health. Her research on osteochondral substitutes was named one of the most important contributions to human healthcare in 2008 by the Literature Awareness System (UK). The commercial development of this innovation by Dr. Tampieri, resulted in a CE marked osteochondral scaffold product, which has been adopted for orthopaedic surgical practice in Europe as the first step toward a completely biologic prosthesis.

The Dr. Tampieri's approach to research is to tackle new and complex problems from a technological perspective. TIME magazine named her research project From Wood to Bone one of 50 most important inventions of 2009. This innovation received worldwide media attention including interviews, articles in specialized and popular magazines, and international TV and radio appearances. The BBC, Sidney Broadcasting News, The Discovery Channel, and Reuter Television have reported on Dr. Tampieri's research initiatives.

Description of Research

Dr. Tampieri's research program focuses on synthesis methodologies, forming methods, sintering processes, and the relationships between microstructural properties and material performance.

Specific initiatives include development of:
-highly porous bioactive bone scaffolds endowed with intrinsic magnetic properties
-biomorphic ceramics with hierarchically organized morphology, derived from the transformation of native ligneous structures for load-bearing applications
-ceramic pastes/cements, designed to exhibit high interconnected porosity and mechanical strength
-bio-hybrid composites based on natural polymers and mineralized with nanostructured biomimetic apatites following biologically inspired processes
-bio-hybrid scaffolds exhibiting mineralization gradients, obtained through interpenetration of bio-hybrid composites for the selective regeneration of bone and osteo-cartilaginous tissues
-organomorphic transformations to obtain three-dimensional polymeric scaffolds that reproduce the morphology and functionality of stromal/vascular systems
-innovative filters for nanoparticles
-recycling technology for nanopowders to reduce environmental toxicity
-intelligent drug delivery systems using nanoparticles driven by magnetic signals

Areas Of Expertise

Biologically inspired processes Bioactive nano-powders Bio-hybrid composites Scaffold for bone and cartilage regeneration Drug delivery
Education & Training

, Government Industrial Research Institute, Nagoya
, Industria Farmitalia-Carlo Erba-Montedison
, National Institute for Inorganic Materials, Tsukuba
, USDA, San Francisco, CA
, University of Bologna
, University of Trento

Novel osteointegrative sr-substituted apatitic cements enriched with Alginate
Sprio, S, Dapporto, M, Montesi, M, Panseri, S, Lattanzi, W, Pola, E, Logroscino, G & Tampieri, A 2016, Materials, vol 9, no. 9, pp. 1-17. DOI:

A novel route for the synthesis of macroporous bioceramics for bone regeneration
Dapporto, M, Sprio, S, Fabbi, C, Figallo, E & Tampieri, A 2016, Journal of the European Ceramic Society, vol 36, no. 9, pp. 2383-2388. DOI:

Development of innovative hybrid and intrinsically magnetic nanobeads as a drug delivery system
Campodoni, E, Adamiano, A, Dozio, SM, Panseri, S, Montesi, M, Sprio, S, Tampieri, A & Sandri, M 2016, Nanomedicine, vol 11, no. 16, pp. 2119-2130. DOI:

Magnetic labelling of mesenchymal stem cells with iron-doped hydroxyapatite nanoparticles as tool for cell therapy
Panseri, S, Montesi, M, Sandri, M, Iafisco, M, Adamiano, A, Ghetti, M, Cenacchi, G & Tampieri, A 2016, Journal of Biomedical Nanotechnology, vol 12, no. 5, pp. 909-921. DOI:

Surface morphology, tribological properties and in vitro biocompatibility of nanostructured zirconia thin films
Bianchi, M, Gambardella, A, Berni, M, Panseri, S, Montesi, M, Lopomo, N, Tampieri, A, Marcacci, M & Russo, A 2016, Journal of Materials Science: Materials in Electronics, vol 27, no. 5, 96. DOI:

Bioinspired negatively charged calcium phosphate nanocarriers for cardiac delivery of MicroRNAs
Di Mauro, V, Iafisco, M, Salvarani, N, Vacchiano, M, Carullo, P, Ramírez-Rodríguez, GB, Patrício, T, Tampieri, A, Miragoli, M & Catalucci, D 2016, Nanomedicine, vol 11, no. 8, pp. 891-906. DOI:

Magnetic forces and magnetized biomaterials provide dynamic flux information during bone regeneration
Russo, A, Bianchi, M, Sartori, M, Parrilli, A, Panseri, S, Ortolani, A, Sandri, M, Boi, M, Salter, DM, Maltarello, MC, Giavaresi, G, Fini, M, Dediu, V, Tampieri, A & Marcacci, M 2016, Journal of Materials Science: Materials in Electronics, vol 27, no. 3, 51, pp. 1-13. DOI:

Tissue Engineering: Biomimetic Concealing of PLGA Microspheres in a 3D Scaffold to Prevent Macrophage Uptake (Small 11/2016)
Minardi, S, Corradetti, B, Taraballi, F, Sandri, M, Martinez, JO, Powell, ST, Tampieri, A, Weiner, BK & Tasciotti, E 2016, Small (Weinheim an der Bergstrasse, Germany), vol 12, no. 11, pp. 1394. DOI:

Needle-like ion-doped hydroxyapatite crystals influence osteogenic properties of PCL composite scaffolds
Guarino, V, Veronesi, F, Marrese, M, Giavaresi, G, Ronca, A, Sandri, M, Tampieri, A, Fini, M & Ambrosio, L 2016, Biomedical Materials (Bristol), vol 11, no. 1, 015018. DOI:

Alendronate functionalized mesoporous bioactive glass nanospheres
Boanini, E, Panseri, S, Arroyo, F, Montesi, M, Rubini, K, Tampieri, A, Covarrubias, C & Bigi, A 2016, Materials, vol 9, no. 3, 135. DOI:

Cermodel 2015: Modelling and Simulation Meet Innovation in Ceramics Technology, July 1-3, 2015, Trento, Italy
Tampieri, A, Bigoni, D & Zannini, P 2016, Journal of the European Ceramic Society. DOI:

Crystallization of citrate-stabilized amorphous calcium phosphate to nanocrystalline apatite: A surface-mediated transformation
Chatzipanagis, K, Iafisco, M, Roncal-Herrero, T, Bilton, M, Tampieri, A, Kröger, R & Delgado-López, JM 2016, CrystEngComm, vol 18, no. 18, pp. 3170-3173. DOI:

Hydroxyapatite: From nanocrystals to hybrid nanocomposites for regenerative medicine
Tampieri, A, Iafisco, M, Sprio, S, Ruffini, A, Panseri, S, Montesi, M, Adamiano, A & Sandri, M 2016, . in Handbook of Bioceramics and Biocomposites. Springer International Publishing, pp. 119-144. DOI:

Nanomechanical mapping of bone tissue regenerated by magnetic scaffolds
Bianchi, M, Boi, M, Sartori, M, Giavaresi, G, Lopomo, N, Fini, M, Dediu, A, Tampieri, A, Marcacci, M & Russo, A 2015, Journal of Materials Science: Materials in Medicine, vol 26, no. 1, pp. 1-9. DOI:

Bio-inspired assembling/mineralization process as a flexible approach to develop new smart scaffolds for the regeneration of complex anatomical regions
Sprio, S, Sandri, M, Iafisco, M, Panseri, S, Adamiano, A, Montesi, M, Campodoni, E & Tampieri, A 2015, Journal of the European Ceramic Society. DOI:

Bioactivity and bone healing properties of biomimetic porous composite scaffold: In vitro and in vivo studies
Veronesi, F, Giavaresi, G, Guarino, V, Raucci, MG, Sandri, M, Tampieri, A, Ambrosio, L & Fini, M 2015, Journal of Biomedical Materials Research - Part A, vol 103, no. 9, pp. 2932-2941. DOI:

Evaluation of the osteoinductive potential of a bio-inspired scaffold mimicking the osteogenic niche for bone augmentation
Minardi, S, Corradetti, B, Taraballi, F, Sandri, M, Van Eps, J, Cabrera, FJ, Weiner, BK, Tampieri, A & Tasciotti, E 2015, Biomaterials, vol 62, pp. 128-137. DOI:

Coupling hydroxyapatite nanocrystals with lactoferrin as a promising strategy to fine regulate bone homeostasis
Montesi, M, Panseri, S, Iafisco, M, Adamiano, A & Tampieri, A 2015, PLoS ONE, vol 10, no. 7, e0132633. DOI:

Synthesis and preliminary in vivo evaluation of well-dispersed biomimetic nanocrystalline apatites labeled with positron emission tomographic imaging agents
Sandhöfer, B, Meckel, M, Delgado-López, JM, Patrício, T, Tampieri, A, Rösch, F & Iafisco, M 2015, ACS Applied Materials and Interfaces, vol 7, no. 19, pp. 10623-10633. DOI:

The efficacy of custom-made porous hydroxyapatite prostheses for cranioplasty: Evaluation of postmarketing data on 2697 patients
Stefini, R, Zanotti, B, Nataloni, A, Martinetti, R, Scafuto, M, Colasurdo, M & Tampieri, A 2015, Journal of Applied Biomaterials and Functional Materials, vol 13, no. 2, pp. E136-E144. DOI: