Alberto Ayala, MD

Professor of Pathology and Genomic Medicine, Institute for Academic Medicine
Full Clinical Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Biography

Shortly after completing a pathology fellowship at the MD Anderson Cancer Center in 1968, he joined the faculty there as an Assistant Professor. He stayed at the institution for 33 years, rising quickly through the academic ranks and earning numerous awards and accolades, including the Charles A. LeMaistre, MD Outstanding Achievement Award in Cancer. Dr. Ayala also held several leadership positions there, including Director of Surgical Pathology, Deputy Chairman of the Department of Anatomic Pathology, and Interim Head of the Division of Pathology. He assumed his current positions at Houston Methodist in 2004.

Description of Research

Dr. Ayala’s research focuses on the pathogenesis of carcinomas of the lung, kidneys and ovaries.

 

 

Areas Of Expertise

Carcinoma Lung Renal
Publications

Sarcoid-like granulomas in renal cell carcinoma: The Houston Methodist Hospital experience
Arora, K, Divatia, MK, Truong, L, Shen, SS, Ayala, AG & Ro, JY 2017, Annals of Diagnostic Pathology, vol 31, pp. 62-65. DOI: 10.1016/j.anndiagpath.2017.07.003

Primary collision tumors of the kidney composed of oncocytoma and papillary renal cell carcinoma: A review
McCroskey, Z, Sim, SJ, Selzman, AA, Ayala, AG & Ro, JY 2017, Annals of Diagnostic Pathology, vol 29, pp. 32-36. DOI: 10.1016/j.anndiagpath.2017.04.011

Human colors-the rainbow garden of pathology: What gives normal and pathologic tissues their color?
Pina-Oviedo, S, Ortiz-Hidalgo, C & Ayala, AG 2017, Archives of Pathology and Laboratory Medicine, vol 141, no. 3, pp. 445-462. DOI: 10.5858/arpa.2016-0274-SA

An isolated inflammatory myofibroblastic tumor of adrenal gland
Al Sannaa, G, Wimmer, JL, Ayala, AG & Ro, JY 2016, Annals of Diagnostic Pathology, vol 25, pp. 33-36. DOI: 10.1016/j.anndiagpath.2016.04.011

Collagenous micronodules in prostate cancer revisited: Are they solely associated with Gleason pattern 3 adenocarcinomas?
Kim, MJ, Divatia, MK, Lee, JH, Shen, S, Miles, BJ, Hwang, JH, Ayala, AG & Ro, JY 2015, International Journal of Clinical and Experimental Pathology, vol 8, no. 4, pp. 3469-3476.

Adenoid cystic carcinoma of breast: Recent advances
Miyai, K, Schwartz, MR, Divatia, MK, Anton, RC, Park, YW, Ayala, AG & Ro, JY 2014, World Journal of Clinical Cases, vol 2, no. 12, pp. 732-41. DOI: 10.12998/wjcc.v2.i12.732

Sclerosing mucoepidermoid carcinoma with eosinophilia of the thyroid: more aggressive than previously reported
Quiroga-Garza, G, Lee, JHY, El-Naggar, A, Black, JO, Amrikachi, M, Zhai, QJ, Ayala, AG & Ro, JY 2015, Human Pathology, vol 46, no. 5, pp. 725-731. DOI: 10.1016/j.humpath.2015.01.012

Metastasizing leiomyoma to heart
Consamus, EN, Reardon, MJ, Ayala, AG, Schwartz, MR & Ro, JY 2014, Houston Methodist DeBakey Cardiovascular Journal, vol 10, no. 4, pp. 251-254. DOI: 10.14797/mdcj-10-4-251

Seminal vesicle intraepithelial involvement by prostate cancer: putative mechanism and clinicopathological significance
Miyai, K, Kristiansen, A, Egevad, L, Pina-Oviedo, S, Divatia, MK, Shen, SS, Miles, BJ, Ayala, AG, Park, YW & Ro, JY 2014, Human Pathology. DOI: 10.1016/j.humpath.2014.05.004

Intraoperative frozen section evaluation of ureteral and urethral margins: studies of 203 consecutive radical cystoprostatectomy for men with bladder urothelial carcinoma
Zhou, H, Ro, JY, Truong, LD, Ayala, AG & Shen, SS 2014, American Journal of Clinical and Experimental Urology, vol 2, no. 2, pp. 156-60.

De novo large cell neuroendocrine carcinoma of the prostate gland with pelvic lymph node metastasis: A case report with review of literature
Okoye, E, Choi, EK, Divatia, M, Miles, BJ, Ayala, AG & Ro, JY 2014, International Journal of Clinical and Experimental Pathology, vol 7, no. 12, pp. 9061-9066.

Calcified amorphous tumor of the heart: case report and review of the literature
Choi, EK, Ro, JY & Ayala, AG 2014, Methodist DeBakey Cardiovascular Journal, vol 10, no. 1, pp. 38-40.

Heterogeneous clinicopathological features of intraductal carcinoma of the prostate: A comparison between 'precursor-like' and 'regular type' lesions
Miyai, K, Divatia, MK, Shen, SS, Miles, BJ, Ayala, AG & Ro, JY 2014, International Journal of Clinical and Experimental Pathology, vol 7, no. 5, pp. 2518-2526.

Diagnostic utility of E-cadherin and P120 catenin cocktail immunostain in distinguishing DCIS from LCIS
Li, X, Schwartz, MR, Ro, J, Hamilton, CR, Ayala, AG, Truong, LD & Zhai, QJ 2014, International Journal of Clinical and Experimental Pathology, vol 7, no. 5, pp. 2551-2557.

Clear cell papillary renal cell carcinoma is the fourth most common histologic type of renal cell carcinoma in 290 consecutive nephrectomies for renal cell carcinoma
Zhou, H, Zheng, S, Truong, LD, Ro, JY, Ayala, AG & Shen, SS 2014, Human Pathology, vol 45, no. 1, pp. 59-64. DOI: 10.1016/j.humpath.2013.08.004

Diagnostic utility of WT-1 cytoplasmic stain in variety of vascular lesions
Galfione, SK, Ro, JY, Ayala, AG & Ge, Y 2014, International Journal of Clinical and Experimental Pathology, vol 7, no. 5, pp. 2536-2543.

Renal sclerosing perivascular epithelioid cell tumor (PEComa)/angiomyolipoma with extensive rhabdoid cell features
Miyai, K, Mullick, SS, Divatia, MK, Shen, SS, Ayala, AG & Ro, JY 2014, Pathology International, vol 64, no. 5, pp. 247-250. DOI: 10.1111/pin.12155

Clinicopathological analysis of intraductal proliferative lesions of prostate: Intraductal carcinoma of prostate, high-grade prostatic intraepithelial neoplasia, and atypical cribriform lesion
Miyai, K, Divatia, MK, Shen, SS, Miles, BJ, Ayala, AG & Ro, JY 2014, Human Pathology, vol 45, no. 8, pp. 1572-1581. DOI: 10.1016/j.humpath.2014.03.011

A study of metastatic carcinoma found in hernia sacs between 2006 and 2012 at one institution
Roberts, JA, Ho, D, Ayala, AG & Ro, JY 2014, Annals of Diagnostic Pathology, vol 18, no. 2, pp. 71-73. DOI: 10.1016/j.anndiagpath.2013.10.008

Tumor-to-tumor metastasis with Endometrial carcinoma metastatic to squamous cell carcinoma of vulva: The first reported case
Wimmer, JL, Coffey, DM, Kaplan, AL, Ayala, AG & Ro, JY 2013, Archives of Pathology and Laboratory Medicine, vol 137, no. 12, pp. 1825-1828. DOI: 10.5858/arpa.2012-0723-CR