Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Elvin Blanco Ph.D.

Elvin Blanco, Ph.D.


Instructor 
Department of Nanomedicine
Houston Methodist Research Institute

E-mail:  eblanco@houstonmethodist.org
Phone: 713-441-7437


Education

M.S.   Case Western Reserve University, OH (Biomedical Engineering)
Ph.D.   UT Southwestern Medical Center, TX (Biomedical Engineering)
     

Postdoctoral Training

Postdoctoral Fellow, Nanomedicine and Biomedical Engineering, UT Health Science Center at Houston, Houston, TX

 

Biography

Elvin Blanco received his B.S. in Biomedical Engineering from Case Western Reserve University (CWRU) in Cleveland, OH in 2002. That same year, he began his graduate training at CWRU in Biomedical Engineering under the mentorship of Dr. Jinming Gao. In 2005, he received his M.S. in Biomedical Engineering from CWRU and relocated to the Simmons Comprehensive Cancer Center at the University of Texas Southwestern Medical Center at Dallas (UTSW). In 2008, he received his Ph.D. in Biomedical Engineering from UTSW. In 2009, Elvin began his postdoctoral training under the mentorship of Dr. Mauro Ferrari at the University of Texas Health Science Center at Houston, working in close collaboration with Dr. Funda Meric-Bernstam in the Department of Surgical Oncology at the University of Texas MD Anderson Cancer Center (UT-MDACC). In 2010, Elvin relocated with Dr. Mauro Ferrari to the Department of Nanomedicine in Houston Methodist Hospital Research Institute, where he serves as a research associate, in close collaboration with UT-MDACC. 

Description of Research

Elvin Blanco’s research involves nanoparticle delivery of chemotherapeutics to enhance synergy in breast cancer. Additional research projects involve delivery of nanotherapeutics for cardiovascular applications in heart failure, myocardial infarction, and atherosclerosis, as well as pulmonary delivery of drugs and genetic materials (e.g., siRNA) for treatment of lung cancer and asthma.

Major Areas of Research

nanoparticle drug delivery, chemotherapeutic synergy, biomaterials, cardiovascular and pulmonary drug delivery, biomaterials

Recent Publications

Ruiz -Esparza GU, Flores-Arredondo JH, Segura-Ibarra V, Torre-Amione G, Ferrari M, Blanco E, Serda RE. The physiology of cardiovascular disease and innovative liposomal platforms for therapy. Int J Nanomedicine. 2013 8:629-40. PMID: 23413209

Blanco E, Hsiao A, Ruiz-Esparza GU, Landry MG, Meric-Bernstam F, Ferrari, M. Molecular-targeted nanotherapies in cancer: Enabling treatment specificity. Mol Oncol. 2011 5(6):492-503. PMID: 22071376

Huan M, Xing G, Blanco E, Wang PC, Liang X, Li X, Song Y, Chen C, Sun B, Yuan H, Zhao F, Chen Z, Sun T, Chai Z, Ferrari M, Zhao Y. Metallofullerene nanoparticles for fibrous imprisonment of tumors. Nanomedicine. 2012 8:136-46. PMID: 21930111

Blanco E, Bey EA, Khemtong C, Yang S, Setti-Guthi J, Chen H, Kessinger CW, Carnevale K,A, Bornmann WG, Boothman DA, Gao J. β-Lapachone micellar nanotherapeutics for non-small cell lung cancer therapy. Cancer Res. 2010 70:3896-904. PMID: 20460521

Yang X, Chen Y, Yuan R, Chen G, Blanco E, Gao J, Shuai X. Folate-encoded and Fe3O4-loaded polymeric micelles for dual targeting of cancer cells. Polymer. 2008 49:3477-85. PMID: 19162315

Dong Y, Chin S-F, Blanco E, Kabbani W, Bey EA, Boothman DA, Gao J. Efficacy of intratumoral β-lapachone polymer millirod implants for prostate cancer treatment. Clin Can Res. 2009 15:131-9. PMID: 19118040

Blanco E, Bey EA, Dong Y, Weinberg BD, Sutton DM, Boothman DA, Gao J. β-Lapachone-containing PEG-PLA polymer micelles as novel nanotherapeutics against NQO1-overexpressing tumor cells. J Control Release. 2007 122:365-74. PMID: 17574288

Wang F, Blanco E, Ai H, Boothman DA, Gao J. Modulating β-lapachone release from polymer millirods through cyclodextrin complexation. J Pharm Sci. 2006 95:2309-19. PMID: 16883563

Blanco E, Weinberg BD, Stowe NT, Anderson JM, Gao J. Local release of dexamethasone from polymer millirods effectively prevents fibrosis following radiofrequency ablation. J Biomed Mat Res A. 2006 76A:174-82. PMID: 16265662