Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Department of Neurosurgery

Christof Karmonik, Ph.D.

Christof Karmonik, Ph.D.

Scientist and MR Physicist
Department of Neurosurgery

Associate Member
Houston Methodist Research Institute

Associate Professor of Physics in Radiology
Weill Cornell Medical College

Phone: 713-441-1583 | Fax: 713-790-6474


Description of Research

Dr. Karmonik’s research has included the effect of lipid modification on peripheral arterial disease, brain volumetric analysis and cognition in Parkinson’s Disease, reliable measurement of brain glutamate levels in ALS patients with 3.0 t 1h-mrs, atherosclerotic plaque composition in peripheral vascular disease, and brain imaging in stuttering.

Major Areas of Research

Peripheral arterial disease, brain volumetric analysis, Parkinson’s Disease, brain imaging


M.S.University of Saarbrucken, Saarbrucken, Germany (Physics)
Ph.D. University of Saarbrucken, Saarbrucken, Germany (Physical Chemistry)

Postdoctoral Training

Postdoctoral Fellowship, The University of Texas M.D. Anderson Cancer Center, Houston, TX

Recent Publications

Karmonik C, Yen C, Diaz O, Klucznik R, Grossman RG, Benndorf G. Temporal variations of wall shear stress parameters in intracranial aneurysms-importance of patient-specific inflow waveforms for CFD calculations. Acta Neurochir (Wien). 2010 Aug;152(8):1391-8.

Karmonik C, Diaz O, Grossman R, Klucznik R. In-Vivo Quantification of Wall Motion in Cerebral Aneurysms from 2D Cine Phase Contrast Magnetic Resonance Images. Rofo. 2010 Feb;182(2):140-50.

Karmonik C, Yen C, Grossman RG, Klucznik R, Benndorf G. Intra-aneurysmal flow patterns and wall shear stresses calculated with computational flow dynamics in an anterior communicating artery aneurysm depend on knowledge of patient-specific inflow rates. Acta Neurochir (Wien). 2009 May;151(5):479-85; discussion 485.

Karmonik C, Basto P, Vickers K, Martin K, Reardon MJ, Lawrie GM, Morrisett JD. Quantitative segmentation of principal carotid atherosclerotic lesion components by feature space analysis based on multicontrast MRI at 1.5 T. IEEE Trans Biomed Eng. 2009 Feb;56(2):352-60.

Karmonik C, Bismuth JX, Davies MG, Lumsden AB. Computational Hemodynamics in the human Aorta: A Computational fluid dynamics study of three cases with patient-specific geometries and inflow rates. Technol Health Ca. 2008 16(5):343-54.

Karmonik C, Klucznik R, Benndorf G. Blood Flow in Cerebral Aneurysms: Comparison of Phase Contrast Magnetic Resonance and Computational Fluid Dynamics - Preliminary Experience. Rofo. 2008 Mar;180(3):209-15.

Mantha A, Karmonik C, Benndorf G, Strother C, Metcalfe R. Hemodynamics in a cerebral artery before and after the formation of an aneurysm. AJNR Am J Neuroradiol. 2006 May;27(5):1113-8.

Choudhary S, Higgins CL, Chen IY, Reardon M, Lawrie G, Vick GW 3rd, Karmonik C, Via DP, Morrisett JD. Quantitation and localization of matrix metalloproteinases and their inhibitors in human carotid endarterectomy tissues. Arterioscler Thromb Vasc Biol. 2006 Oct;26(10):2351-8.

Karmonik C, Strother CM, Chen X, Deinzer F, Klucznik R, Mawad ME. Stent-assisted coiling of intracranial aneurysms aided by Virtual Parent Artery Reconstruction: Technical Note. AJNR Am J Neuroradiol. 2005 26:2368-2370.