Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Methodist J.C. Walter Jr. Transplant Center - Houston, TX

Current/On-going Research

Dr. Brian Bruckner

Total: 20 projects

  1. Retrospective Chart Review in Cardiac Tumor Patients
    Sub-Investigator (PI: Shanda Blackmon, M.D.)
    04/2007 – Present

  2. Study of Myocardial Structure and Function in Patients with End
    Stage Heart Failure in Need of Mechanical Circulatory Support
    Sub-Investigator (PI: Guillermo Torre-Amione)
    09/2007 - present

  3. Evaluation of the VentrAssist™ Left Ventricular Assist Device as a Bridge to Cardiac Transplantation-Pivotal Trial
    Sub-Investigator (PI: Guillermo Torre-Amione).
    Ventracor, Inc.
    11/2007 – present

  4. Evaluation of the VentrAssist™ Left Ventricular Assist Device for the Treatment of Advanced Heart Failure – Destination Therapy
    Sub-Investigator (PI: Guillermo Torre-Amione)
    Ventracor, Inc
    04/2008- Present

  5. Intramyocardial Delivery of Autologous Bone Marrow Cells in Patients with Heart Failure Due to Dilated Cardiomyopathy
    (PI: Brian Bruckner)
    Aastrom Biosciences, Inc.
    09/2008 – Present

  6. A Randomized, Controlled, Phase 3 Study of Gentamicin-Collagen Sponge (Collatamp® G) in Cardiac Surgical Subjects at Higher Risk for Sternal Wound Infection. Sub-Investigator
    (PI: Michael Reardon, M.D.)
    Innocoll Technologies, Ltd.
    09/2008 – Present

  7. A Phase I, Randomized, Double-Blinded, Dose Escalation Trial of the Safety and Pharmacokinetics of a Single Intravenous Injection of I5NP in Patients at High Risk for Acute Kidney Injury Undergoing Major Cardiovascular
    Surgery. Sub-Investigator (PI: Michael Reardon, M.D.)
    Quark Pharmaceuticals, Inc.
    09/2008 – Present

  8. Victoria Multi-Center Clinical Registry Protocol: Visual Interpretation of Completeness and Technical Operative Results using Intra-operative Arteriography.
    Sub-Investigator (PI: Mahesh Ramchandani, M.D.)
    Novadaq Technologies, Inc and East Carolina University
    10/2008 – Present

  9. Carotid Artery Plaques of Advanced Atherosclerosis: Comprehensive Histopathology and Diagnosis.
    Sub-Investigator (PI: Michael Reardon, M.D.)
    10/2008 – Present

  10. Histologic correlates of delayed enhancement cardiac magnetic resonance (CMR) in ischemic and nonischemic cardiomyopathies
    Sub-Investigator (PI: Dipan Shah, M.D.)
    10/2008 – Present

  11. On-Pump" CABG Embolus Detection & Monitoring Project
    Sub-Investigator (PI: Michael Reardon, M.D.)
    11/2008 – Present

  12. Autologous, Percutaneously Implantable Tissue Engineered Aortic Valve
    Sub-Investigator (PI: Jane Grande-Allen, Ph.D & Erik Beyer, M.D.)
    Simmons Family Foundation

  13. Investigator HeartWare LVAD trial
    to start 06/2009

  14. “Reversal of pulmonary hypertension with left ventricular assist devices”

  15. “Use of Recombinant Factor VII in high risks patients undergoing cardiac Surgery”

  16. “Use of the Tandem Heart percutaneous ventricular assist device in heart failure patients undergoing cardiac surgical procedures”

  17. The Effect Of Acadesine On Clinically Significant Adverse Cardiovascular and Cerebrovascular Events In High-Risk Subjects Undergoing Coronary Artery Bypass Graft (CABG) Surgery Using Cardiopulmonary Bypass (Protocol No. P05633): RED–CABG Trial (Reduction in Cardiovascular Events by AcaDesine in Subjects Undergoing CABG)
    PI: Brian Bruckner
    Start 04/2009

  18. “Myocardial remodeling during left ventricular assist device support”
    7/1/07 – present, Brian Bruckner

  19. “Histologic and molecular markers of myocardial improvement following Prolonged ventricular support”
    7/1/07 – present, Brian Bruckner

  20. Aastrom multicenter Cardiac Stem Cell Trial (PI at Methodist Hospital)