Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Research

Research

Because of Houston Methodist's academic affiliation with Weill Cornell Medical College of Cornell University and the establishment of Houston Methodist Research Institute (TMHRI), the Department of Anesthesiology is in a unique position to conduct groundbreaking research activity. Please read on for some of our recent research, publications and presentations.

2007 Research

Safety Aspects of Mobilizing Patients with Femoral Arterial Lines (Retrospective Review) P.I. Faisal Masud, M.D., Sub-Investigator, Christiane Perme, IRB Approved: Feb 2006-2007

Recombinant Factor VIIa Treatment for Severe Bleeding in post HEART TRANSPLANT and ventricular assist device implantation Surgery Patients: A retrospective analysis of safety and outcomes over a 3 year period. P.I. Faisal Masud, M.D.

A Study to Assess the Feasibility, Prevalence and Correlates of Post-Traumatic Stress Disorder Symptoms of Critical Care Nurses. Co-Investigator, Faisal Masud, M.D.

Recombinant Factor Vlla Use in the Treatment of Severe Post Cardiac Surgical Bleeding (Retrospective Review) P.I. Faisal Masud, M.D.; Data collection and analysis complete, paper pending

A Prospective, Observational Study of Heparin-Induced Thrombocytopenia Following Cardiovascular Surgery. P.I. Faisal Masud, M.D.

A Multi-Center, randomized, Double-blind, placebo-controlled, dose escalation trial on safety and efficacy of activated recombinant Factor VII (rFVIIa/NovoSeven) in the treatment of post-operative bleeding in patients following cardiac surgery requiring cardiopulmonary bypass. P.I. Luis Velez, M.D.

A Multi-Center, randomized, Double-blind, placebo-controlled, dose escalation trial on safety and pharmacokinetics of recombinant Factor XIII (rFXIII) in patients following first time myocardial revascularization requiring cardiopulmonary bypass. P.I. Luis Velez, M.D.

DX-88 (Ecallantide) for the Reduction of Blood Loss Associated with Cardiopulmonary Bypass: A Phase 2 Randomized, Double-Blind, Placebo-Controlled, Multi-center Study in Patients Undergoing Primary Coronary Artery Bypass Grafting, Single Valve Repair or Single Valve Replacement. P.I. Luis Velez, M.D.

Publications

"Clinical Brief: Early Placement of Extracorporeal Membrane Oxygenation: A Suitable Alternative for Patients with Severe Cardiopulmonary Failure." Journal of the Houston Methodist DeBakey Heart Center. 2007; 3(1): 22-24. Zaidi S, Krinock S, Ramchandani M, Loebe M, Naples J.

"Cardiac autotransplantation for surgical resection of a primary malignant left ventricular tumor." Texas Heart Institute Journal. 2006; 33(4): 495-7. Reardon MJ, Walkes JC, DeFelice CA, Wojciechowski Z.

"Rapid reversal of Warfarin toxicity using recombinant factor VIIa in a deteriorating patient with left hemothorax." Journal of Special Operations Medicine. 2007; 7(3): 42-44. Samir H, Owens G, Masud F.

"Adverse Drug Reactions in Patients with Phaeochromocytoma." Drug Safety. 2007; 32 (11): 1031-1062. Eisenhofer G, Rivers G, Rosas A, Quezado Z, Manger W, Pacak C.

"Glucocorticoids may induce pheochromocytoma crises." Journal of Human Hypertension. 2008; 22(1): S10. Rosas AL, Kasperlik-Zaluska AA, Papierska L, Bass BL, Pacak K, Eisenhofer G.

"PT.1. Pheochromocytoma multisystem crisis: management of a patient presenting with cardiogenic shock." Journal of Human Hypertension. 2008; 22(1): S13. Rosas AL, Bass BL, Hamilton DJ.

"Response to aspirin and clopidogrel in patients schedule to undergo cardiovascular surgery." Journal of Thromb Thombolysis. 2007; 24(1): 15-21. Lev EI, Ramchandani M, Garg R, Wojciechowski Z, Builes A, Vaduganathan M, Tripathy U, Kleiman NS.

"Update on blood transfusion in cardiac surgical patients." Journal of the Houston Methodist DeBakey Heart Center. 2007; 3(1): 10-12. Masud F.

"ICU Pain, Anxiety, Agitation, Delirium: In Search for the Holy Grail." Journal of the Houston Methodist DeBakey Heart Center. 2007; 3(1): 13-17. Thaker K.

"Perioperative Glucose Control and Cardiovascular Complications of the Cardiac Patient." Journal of the Houston Methodist DeBakey Heart Center. 2007; 3(1): 18-21. Athanassiou N.

"It's Time for the Operation: what to expect before, during and after surgery for pheochromocytoma." 2008 Final Programme of 2nd International Symposium on Pheochromocytoma, Queen's College, Cambridge, UK. September 2008. Rosas, AL.

"Cardiac autotransplantation for primary cardiac tumors." Annals of Thoracic Surgery. August 2006; 82(2): 645-50. Reardon MJ, Malaisrie SC, Walkes JC, Vaporciyan AA, Rice DC, Smythe WR, DeFelice CA, Wojciechowski Z.

"Transesophageal echocardiography for mitral valve repair surgery." Journal of the Houston Methodist DeBakey Heart Center. 2006; 2(3): 19. Herrera EL, Lawrie GM.

Presentations

"Glucocorticoids may induce pheochromocytoma crises." 2nd International Symposium on Pheochromocytoma, Queens' College, Cambridge, UK, Sept. 2008. AL Rosas, Papierska Kasperlik-Zaluska, BL Bass, Pacak BL, Eisenhofer K.

PT.01 " Pheochromocytoma multisystem crisis: management of a patient presenting with cardiogenic shock." 2nd International Symposium on Pheochromocytoma, Queens' College, Cambridge, UK, Sept. 2008. AL Rosas, BL Bass, DJ Hamilton.

"PT.02 "Ockham's Razor and the Chameleon: a cerebellar mass, headache, and hypertension. Is it a Pheochromocytoma? AL Rosas, TA Aloia, BJ Dunkin, PJ Yeh, DJ Hamilton.

"It's time for the operation: what to expect before, during, and after surgery for pheochromocytoma. 2nd International Symposium on Pheochromocytoma, Queens' College, Cambridge, UK, Sept. 2008. AL Rosas.