Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Yuriy Fofanov Ph.D.

Yuriy Fofanov, Ph.D.

Yuriy Fofanov, Ph.D.

Affiliate Member
The Methodist Hospital Research Institute
Associate Professor, College of Natural Sciences and Mathematics
Director, UH Bioinformatics Laboratory
University of Houston

E-mail: yfofanov@uh.edu
Phone: 713-743-8553


Education

M.S.c.   Kuibyshev (Samara) State University, USSR (Physics)
Ph.D.   Kuibyshev (Samara) State University, USSR (Physics and Mathematics)
 

Biography

Dr. Fofanov received his first academic appointment in 1989, as a Head of the Lab in the Russian Academy of Science. He joined the faculty in the Department of Computer Science at the University of Houston as an Assistant Professor in 2001. At present, Dr. Fofanov holds two faculty appointments in the College of Natural Sciences; Associate Professor, Department of Computer Science, and Associate Professor, Department of Biology and Biochemistry. He is also a faculty member at the W.M. Keck Center for Computational and Structural Biology.

Dr. Fofoanov has published numerous peer-reviewed papers in the literature, and has been the principal investigator on four research grants funded by the Homeland Security Advanced Research Projects Agency.

Description of Research

Dr. Fofanov’s research centers on population-scale HLA typing, and tools for ultraspecific probe/primer design. His bioinformatics research specifically focuses on gene expression, including investigations into micro-array data normalization approaches, and genomic sequence analysis, which includes studies of the statistical properties of short subsequences in microbial and viral genomes.

Major Areas of Research

Bioinformatics, computer science, applied statistics.

Recent Publications

Anez ML, Putonti C, Fox GE, Fofanov Y, Willson RC. Exhaustive computational identification of pathogen sequences far-distant from background genomes: identification and experimental verification of human-blind Dengue PCR primers. J Biotechnol. 2008; 133(3):267-276.

Reed C, Fofanov V, Putonti C, Slezak T, Fofanov Y. Computational modeling of the effect of the background size on the quality of pathogen identification. Bioinformatics. 2007;23(20):2665-2671.

Tucker DL, Ott CM, Huff S, Fofanov Y, Pierson DL, Willson RC, Fox GE. Characterization of Escherichia coli MG 1655 grown in a low-shear modeled microgravity environment. BMC Microbiol. 2007; 7:15.

Putonti C, Luo Y, Katili C, Chumakov S, Fox GE, Graur D, Fofanov Y. A computational tool for the genomic identification of regions of unusual compositional properties and its utilization in the detection of horizontally transferred sequences. Mol Biol Evol. 2006; 23(10):1863-1868.

Putonti C, Chumakov S, Mitra R, Fox GE, Willson RC, Fofanov Y. Human-blind probes and primers for dengue virus identification. FEBS J. 2006; 273(2): 398-408.