Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Michael J. Thrall


Michael J. Thrall, MD

Michael J. Thrall, MD

Medical Director, Digital Pathology
Department of Pathology and Genomic Medicine
Houston Methodist Hospital Physicians Organization
Assistant Member
Houston Methodist Research Institute
Assistant Professor of Pathology and Laboratory Medicine
Weill Cornell Medical College of Cornell University

6565 Fannin Street, Suite M227
Houston, Texas 77030
Phone: 713—441-4459
E-mail: mjthrall@houstonmethodist.org


Dr. Thrall received his M.D. degree from the University of Minnesota Medical School in Minneapolis in 2003. He remained at the University and completed his AP/CP residency training, including a surgical pathology fellowship. Dr. Thrall then went on to a cytopathology fellowship at the University of Rochester in Rochester, New York before joining The Methodist Hospital Physician Organization and Weill Cornell Medical College in 2008.

Dr. Thrall is a general surgical pathologist and cytopathologist with subspecialty interests in gynecologic, lung, and head and neck pathology. His primary research interests are focused in cytopathology. He is also working with the Department of Radiology and Research Institute to develop new approaches to the diagnostic interface between radiology and pathology.

Representative Recent Publications

  • Thrall MJ, Galfione SK, Smith DA. The impact of LSIL-H terminology on patient follow-up patterns: A comparison with LSIL and ASC-H. Diagn Cytopathol. 2013 Apr 3. [Epub ahead of print]
  • Stamatakis L, Cheng PJ, Ho PL, Thrall MJ, Mayer WA, Miles BJ, Link RE. A 60-year-old woman with an incidentally discovered right renal mass. Urology. 2012 Dec;80(6):1183-6.
  • Gao L, Wang Z, Li F, Hammoudi AA, Thrall MJ, Cagle PT, Wong ST. Differential diagnosis of lung carcinoma with coherent anti-Stokes Raman scattering imaging. Arch Pathol Lab Med. 2012 Dec;136(12):1502-10.
  • Mishra DK, Sakamoto JH, Thrall MJ, Baird BN, Blackmon SH, Ferrari M, Kurie JM, Kim MP. Human lung cancer cells grown in an ex vivo 3D lung model produce matrix metalloproteinases not produced in 2D culture. PLoS One. 2012;7(9):e45308.
  • Khan KA, Smith DA, Thrall MJ. Only a Small Fraction of High-Grade Cervical Lesions Are Discovered After an Interpretation of Atypical Squamous Cells of Undetermined Significance When Using Imager-Assisted, Liquid-Based Papanicolaou Tests and the Bethesda 2001 System. Arch Pathol Lab Med. 2012 Sep 20. [Epub ahead of print]
  • Gao L, Hammoudi AA, Li F, Thrall MJ, Cagle PT, Chen Y, Yang J, Xia X, Fan Y, Massoud Y, Wang Z, Wong ST. Differential diagnosis of lung carcinoma with three-dimensional quantitative molecular vibrational imaging. J Biomed Opt. 2012 Jun;17(6):066017.
  • Mishra DK, Thrall MJ, Baird BN, Ott HC, Blackmon SH, Kurie JM, Kim MP. Human Lung Cancer Cells Grown on Acellular Rat Lung Matrix Create Perfusable Tumor Nodules. Ann Thorac Surg. 2012 Apr;93(4):1075-81.
  • Pambuccian SE, Stelow EB, Koutlas IG, Thrall MJ. Head and neck pathology: new developments in the diagnosis and pathogenesis of head and neck tumors. Patholog Res Int. 2011;2011:354747.
  • Thrall M, Pantanowitz L, Khalbuss W. Telecytology: Clinical applications, current challenges, and future benefits. J Pathol Inform. 2011;2:51.
  • Zarrin-Khameh N, Haas EM, Ro J, Thrall MJ. Lipomatosis coli, a mimicker of familial polyposis. Ann Diagn Pathol. 2011 Nov 4. [Epub ahead of print]
  • Gao L, Li F, Thrall MJ, Yang Y, Xing J, Hammoudi AA, Zhao H, Massoud Y, Cagle PT, Fan Y, Wong KK, Wang Z, Wong ST. On-the-spot lung cancer differential diagnosis by label-free, molecular vibrational imaging and knowledge-based classification. J Biomed Opt. 2011 Sep;16(9):096004.
  • Yang Y, Li F, Gao L, Wang Z, Thrall MJ, Shen SS, Wong KK, Wong ST. Differential diagnosis of breast cancer using quantitative, label-free and molecular vibrational imaging. Biomed Opt Express. 2011 Aug 1;2(8):2160-74.
  • Gao L, Zhou H, Thrall MJ, Li F, Yang Y, Wang Z, Luo P, Wong KK, Palapattu GS, Wong ST. Label-free high-resolution imaging of prostate glands and cavernous nerves using coherent anti-Stokes Raman scattering microscopy. Biomed Opt Express. 2011 Mar 18;2(4):915-26.
  • Mody DR, Nayar R, Thrall M. 2001 Bethesda system classification of glandular lesions on cervical cytology. Monogr Clin Cytol. 2011;20:5-14.
  • Koen TM, Mody DR, Scheiber-Pacht M, Fairley T, Thrall MJ. Limiting the use of atypical/inconclusive as a category in nongynecologic cytology specimens. Arch Pathol Lab Med. 2010 Jul;134(7):1016-9.
  • Thrall MJ, Russell DK, Facik MS, Yao JL, Warner JN, Bonfiglio TA, Giampoli EJ. High-risk HPV testing in women 30 years or older with negative Papanicolaou tests: initial clinical experience with 18-month follow-up. Am J Clin Pathol. 2010 Jun;133(6):894-8.
  • Thrall MJ, Smith DA, Mody DR. Women >or=30 years of age with low grade squamous intraepithelial lesion (LSIL) have low positivity rates when cotested for high-risk human papillomavirus: should we reconsider HPV triage for LSIL in older women? Diagn Cytopathol. 2010 Jun;38(6):407-12.
  • Thrall MJ, Giampoli EJ. Routine review of ascites fluid from patients with cirrhosis or hepatocellular carcinoma is a low-yield procedure: an observational study. Cytojournal. 2009 Aug 7;6:16.
  • Thrall MJ, Pambuccian SE, Stelow EB, McKeon DM, Miller L, Savik K, Gulbahce HE. Impact of the more restrictive definition of atypical squamous cells introduced by the 2001 Bethesda System on the sensitivity and specificity of the Papanicolaou test: a 5-year follow-up study of Papanicolaou tests originally interpreted as ASCUS, reclassified according to Bethesda 2001 criteria. Cancer. 2008 Jun 25;114(3):171-9.
  • Thrall MJ, Russell DK, Bonfiglio TA, Hoda RS. Use of the ThinPrep Imaging System does not alter the frequency of interpreting Papanicolaou tests as atypical squamous cells of undetermined significance. Cytojournal. 2008 Apr 24;5:10.
  • Thrall MJ, Kjeldahl KS, Savik K, Gulbahce HE, Pambuccian SE. Significance of benign endometrial cells in papanicolaou tests from women aged >or=40 years. Cancer. 2005 Aug 25;105(4):207-16.