Mr. Mehta received his Master of Science degree from Virginia Commonwealth University in Richmond, VA in 2011. He is currently pursuing a Ph.D. in Biomedical Sciences at the Baylor College of Medicine and working in the laboratory of Dr. Adriana Rosato at The Methodist Hospital Research Institute.
Mr. Mehta is investigating the genetic basis of drug resistance in Staphylococcus aureus at the molecular level. His current studies are specifically focused on elucidating the molecular changes that cause S. aureus strains to become resistant to daptomycin.
Staphylococcus aureus, gene expression, drug resistance
Mehta S, Singh C, Plata KB, Chanda PK, Paul A, Riosa S, Rosato RR, Rosato AE. ß-lactams increase the antibacterial activity of daptomycin against clinical MRSA strains and prevent selection of DAP-resistant derivatives. Antimicrob Agents Chemother. 2012 Sep 17. [Epub ahead of print]
Mehta S, Cuirolo AX, Plata KB, Riosa S, Silverman JA, Rubio A, Rosato RR, Rosato AE. VraSR two-component regulatory system contributes to mprF-mediated decreased susceptibility to daptomycin in in vivo-selected clinical strains of methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2012 Jan;56(1):92-102.