Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Sheldon L. Kaplan M.D.

Sheldon L. Kaplan, M.D.

Sheldon L. Kaplan, M.D.

Senior Affiliate Member
The Methodist Hospital Research Institute
Chief, Infectious Disease Service
Texas Children’s Hospital
Professor and Vice Chairman for Clinical Affairs, Department of Pediatrics
Head, Pediatric Infectious Diseases Section
Baylor College of Medicine

Phone: 832-824-4330
Fax: 832-825-4347
E-mail: skaplan@bcm.edu


B.A.   University of Missouri, Columbia, MO (Chemistry)
M.D.   University of Missouri School of Medicine, Columbia, MO

Postdoctoral Training

Pediatric Residency, St. Louis Children’s Hospital/Washington University School of Medicine, St. Louis, MO
Pediatric Infectious Diseases Fellowship, St. Louis Children’s Hospital/Washington University School of Medicine, St. Louis, MO



After completing his postdoctoral training in 1977, Dr. Kaplan joined the faculty at the Baylor College of Medicine in Houston, Texas as an Assistant Professor in the Department of Pediatrics. He became the chief of the Infectious Disease Service at the Texas Children’s Hospital in 1981, and a full professor at Baylor in 1987. Dr. Kaplan holds several leadership positions in the Department of Pediatrics at Baylor including Professor and Vice Chairman for Clinical Affairs and head of the Pediatric Infectious Diseases Section.

Description of Research

Dr. Kaplan conducts clinical surveillance studies of invasive infections in children. He is also sequencing the predominant clone of community-acquired methicillin-resistant S. aureus (MRSA) in Houston (USA300-HOU) to discover S. aureus epitopes for potential vaccine candidates.

Major Areas of Research

Infectious diseases, S. pneumoniae, N. meningitides, S. aureus, gene sequencing.

Recent Publications

Hult KG, Kaplan SL, Lamberth LB, Slimp K, Hammerman WA, Carrillo-Marquez M, Starke JR, Versalovic J, Mason EO Jr. Hospital-acquired Staphylococcus aureus infections at Texas Children’s Hospital, 2001-2007. Infect Control Hosp Epidemiol. 2010 Feb;31(2):183-90.

Carrillo-Marquez MA, Hulten KG, Hammerman W, Mason EO, Kaplan SL. USA300 is the predominant genotype causing Staphylococcus aureus septic arthritis in children. Pediatr Infect Dis J. 2009 Dec;28(12):1076-80.

McNeil JC, Hulten KG, Mason EO Jr, Kaplan SL. Serotype 19A is the most common Streptococcus pneumoniae isolate in children with chronic sinusitis. Pediatr Infect Dis J. 2009 Sep;28(9):766- 8.

Mason EO, Lamberth LB, Hammerman WA, Hulten KG, Versalovic J, Kaplan SL. Vancomycin MICs for Staphylococcus aureus vary by detection method and have subtly increased in a pediatric population since 2005. J Clin Microbiol. 2009 Jun;47(6):1628-30.

Kaplan SL. Challenges in the evaluation and management of bone and joint infections and the role of new antibiotics for gram positive infections. Adv Exp Med Biol. 2009;634:111-20.