Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Medicinal and Radiopharmaceutical Chemistry Lab

Research - Medicinal and Radiopharmaceutical Chemistry Lab


Zheng Li, Ph.D.


Pardip Ghosk, Ph.D.
Feng Li, Ph.D.
Guting Qin, Ph.D.

Mission Statement

The goal of our research program is to bring the power of modern synthetic and medicinal chemistry combined with radiopharmaceutical chemistry to develop new biomedical imaging and therapeutic agents.

Research Interests

  • Developing novel molecular imaging agents to visualize specific molecular targets and pathways in live cells, tissues and organism and to better understand and provide early diagnosis of human diseases, particularly for cancer and neurodegeneration using Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT).
  • Developing new bioactive molecules based on biomechanistic rationale and the structural optimization to discover new therapeutic agents for cancer.
  • Developing new drug delivery systems by using smart designed targeted nano-particles combined with multimodality imaging and ultrasound technique.


Our facilities are equipped to conduct radiolabeling procedures with Fluorine-18, Technetium-99m and Indium-111. We have chemical synthesis, chemical analysis and nanoparticle characterization capabilities (High Performance Liquid Chromotography, Flash Chromatography Automation System, Microwave Synthesizer, Mass Spectrometry and Zetasizer Nano-ZS).