Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Map & Directions

Contact Us

Houston Methodist Outpatient Center
6445 Main Street
Houston, TX 77030

Phone: 713-790-3311

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Directions to our facility

We are located in the Texas Medical Center, just southwest of downtown Houston. Listed below are directions from all major airports and freeways to our facility.

Airports

From Bush Intercontinental Airport: Exit Bush Intercontinental Airport via Will Clayton Boulevard toward Highway 59. Take Highway 59 South approximately 19 miles to Highway 288 South. From 288 exit MacGregor Drive. At MacGregor turn right. At Holcombe Blvd. turn right. Continue to Main Street. At Main Street turn right. Continue to John Freeman Blvd. Turn right on John Freeman. Houston Methodist Hospital Outpatient Center is located at Main Street and John Freeman.

From Houston Hobby Airport: From the airport exit Broadway. Travel Broadway to I-45 North. Take I-45 North to the 610 West Loop. Continue on the 610 West Loop until the Main Street exit. Take this exit and turn right on Main. Drive for approximately two miles to John Freeman Blvd. Turn right on John Freeman. Houston Methodist Hospital Outpatient Center is located at Main Street and John Freeman.

Freeway Access

From North Houston: Take I-45 South to Highway 288 South. Take the MacGregor exit. At MacGregor turn right. At Holcombe Blvd. turn right. Continue to Main Street. At Main Street turn right. Continue to John Freeman Blvd. Turn right on John Freeman. Houston Methodist Hospital Outpatient Center is located at Main Street and John Freeman.

From the Northeast: Take 59 South to Highway 288 South. Take the MacGregor exit. At MacGregor turn right. At Holcombe Blvd. turn right. Continue to Main Street. At Main Street turn right. Continue to John Freeman Blvd. Turn right on John Freeman. Houston Methodist Hospital Outpatient Center is located at Main Street and John Freeman.

From the Northwest: Travel Highway 290 South to the 610 West Loop South. Continue along the 610 Loop to the Main Street exit. Turn left on Main and continue for approximately two miles. Turn right on John Freeman. Houston Methodist Hospital Outpatient Center is located at Main Street and John Freeman.

From South Houston: Take I-45 North until the 610 Loop West. Take the 610 Loop West to the Fannin Street exit. Take this exit and turn right on Fannin. Drive for approximately two miles to John Freeman Blvd. Turn right on John Freeman. Houston Methodist Hospital Outpatient Center is located at Main Street and John Freeman.

From the Southeast: Take Highway 225 to I-45 North. Take I-45 North to 59 South and then take Highway 288 South. Take the MacGregor exit. At MacGregor turn right. At Holcombe Blvd. turn right. Continue to Main Street. At Main Street turn right. Continue to John Freeman Blvd. Turn right on John Freeman. Houston Methodist Hospital Outpatient Center is located at Main Street and John Freeman.

From the Southwest: Take 59 North to Highway 288 South. Take the MacGregor exit. At MacGregor turn right. At Holcombe Blvd. turn right. Continue to Main Street. At Main Street turn right. Continue to John Freeman Blvd. Turn right on John Freeman. Houston Methodist Hospital Outpatient Center is located at Main Street and John Freeman.

From East Houston: Take I-10 West to 59 South. From 59 South take 288 South. Take the MacGregor exit. At MacGregor turn right. At Holcombe Blvd. turn right. Continue on Holcombe to Main Street. At Main Street turn right. Continue to John Freeman Blvd. Turn right on John Freeman. Houston Methodist Hospital Outpatient Center is located at Main Street and John Freeman.

From West Houston: Take I-10 East to I-45 South. Take I-45 South to 288 South. Take the MacGregor exit. At MacGregor turn right. At Holcombe Blvd. turn right. Continue on Holcombe to Main Street. At Main Street turn right. Continue to John Freeman Blvd. Turn right on John Freeman. Houston Methodist Hospital Outpatient Center is located at Main Street and John Freeman.