Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Konrad B. Plata Ph.D.

 

Konrad B. Plata, Ph.D.

Postdoctoral Fellow
The Methodist Hospital Research Institute

E-mail: kbplata@houstonmethodist.org   
Phone: 713-441-7118                                                           

Education

M.Sc. University of Gdansk, Gdansk, Poland (Microbiology/Molecular Biology)
Ph.D.   University of Gdansk, Gdansk, Poland (Microbiology)

Postdoctoral Training

Postdoctoral Fellowship, Center for Molecular and Translational Human Infectious Diseases Research, The Methodist Hospital Research Institute, Houston, TX

Biography

Dr. Plata received his Ph.D. in Microbiology from the University of Gdansk in Gdansk, Poland in 2010. The doctoral program was part of a collaboration between the University of Gdansk and Virginia Commonwealth University in Richmond, VA. During his doctoral program, Dr. Plata studied under the mentorship of Dr. Adriana Rosato at Virginia Commonwealth. He received a First Class Award for his doctoral thesis on homogenous ß-lactam resistance in methicillin-resistant Staphylococcus aureus strains. Dr. Plata remained in Dr. Rosato's laboratory to pursue his postdoctoral studies.

Description of Research

Dr. Plata’s research focus is on investigations of the molecular pathogenesis of ß-lactam resistance in methicillin-resistant Staphylococcus aureus (MRSA).

Major Areas of Research

Methicillin-resistant Staphylococcus aureus (MRSA), drug resistance, gene expression, agr, vraSR, mprF

Recent Publications

Mehta S, Singh C, Plata KB, Chanda PK, Paul A, Riosa S, Rosato RR, Rosato AE. ß-lactams increase the antibacterial activity of daptomycin against clinical MRSA strains and prevent selection of DAP-resistant derivatives. Antimicrob Agents Chemother. 2012 Sep 17. [Epub ahead of print]

Mehta S, Cuirolo AX, Plata KB, Riosa S, Silverman JA, Rubio A, Rosato RR, Rosato AE. VraSR two-component regulatory system contributes to mprF-mediated decreased susceptibility to daptomycin in in vivo-selected clinical strains of methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2012 Jan;56(1):92-102.

Plata KB, Rosato RR, Rosato AE. Fate of Mutation Rate Depends on agr Locus Expression during Oxacillin-Mediated Heterogeneous-Homogeneous Selection in Methicillin-Resistant Staphylococcus aureus Clinical Strains. Antimicrob Agents Chemother. 2011 Jul;55(7):3176-86.