Konrad B. Plata, Ph.D.
Postdoctoral Fellowship, Center for Molecular and Translational Human Infectious Diseases Research, The Methodist Hospital Research Institute, Houston, TX
Dr. Plata received his Ph.D. in Microbiology from the University of Gdansk in Gdansk, Poland in 2010. The doctoral program was part of a collaboration between the University of Gdansk and Virginia Commonwealth University in Richmond, VA. During his doctoral program, Dr. Plata studied under the mentorship of Dr. Adriana Rosato at Virginia Commonwealth. He received a First Class Award for his doctoral thesis on homogenous ß-lactam resistance in methicillin-resistant Staphylococcus aureus strains. Dr. Plata remained in Dr. Rosato's laboratory to pursue his postdoctoral studies.
Dr. Plata’s research focus is on investigations of the molecular pathogenesis of ß-lactam resistance in methicillin-resistant Staphylococcus aureus (MRSA).
Methicillin-resistant Staphylococcus aureus (MRSA), drug resistance, gene expression, agr, vraSR, mprF
Mehta S, Singh C, Plata KB, Chanda PK, Paul A, Riosa S, Rosato RR, Rosato AE. ß-lactams increase the antibacterial activity of daptomycin against clinical MRSA strains and prevent selection of DAP-resistant derivatives. Antimicrob Agents Chemother. 2012 Sep 17. [Epub ahead of print]
Mehta S, Cuirolo AX, Plata KB, Riosa S, Silverman JA, Rubio A, Rosato RR, Rosato AE. VraSR two-component regulatory system contributes to mprF-mediated decreased susceptibility to daptomycin in in vivo-selected clinical strains of methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2012 Jan;56(1):92-102.
Plata KB, Rosato RR, Rosato AE. Fate of Mutation Rate Depends on agr Locus Expression during Oxacillin-Mediated Heterogeneous-Homogeneous Selection in Methicillin-Resistant Staphylococcus aureus Clinical Strains. Antimicrob Agents Chemother. 2011 Jul;55(7):3176-86.