Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Donna M. Coffey


Donna M. Coffey, M.D.

Donna M. Coffey, MD

Staff Pathologist
Department of Pathology and Genomic Medicine
Houston Methodist Hospital Physicians Organization
Assistant Professor of Pathology and Laboratory Medicine
Weill Cornell Medical College of Cornell University

6565 Fannin Street, Suite M227
Houston, Texas 77030
Phone: 713-441-4471
Email: dcoffey@houstonmethodist.org


Dr. Coffey obtained her M.D. degree from the University of Costa Rica in San Jose in 1991. She then completed a pathology residency and cytopathology fellowship at the Baylor College of Medicine in Houston, Texas before joining the faculty at Baylor as an assistant professor in the Department of Pathology.

Dr. Coffey is a general surgical pathologist with subspecialty training in cytopathology. Her areas of interest are gynecologic pathology and cytopathology. She is currently involved in several collaborative studies using tissue microarrays of gynecologic malignancies.

Representative Recent Publications

  • Hawkins SM, Loomans HA, Wan YW, Ghosh-Choudhury T, Coffey D, Xiao W, Liu Z, Sangi-Haghpeykar H, Anderson ML. Expression and Functional Pathway Analysis of Nuclear Receptor NR2F2 in Ovarian Cancer. J Clin Endocrinol Metab. 2013 May 20. [Epub ahead of print]
  • Wright AM, Smith D, Dhurandhar B, Fairley T, Scheiber-Pacht M, Chakraborty S, Gorman BK, Mody D, Coffey DM. Digital Slide Imaging in Cervicovaginal Cytology: A Pilot Study. Arch Pathol Lab Med. 2013 May;137(5):618-24.
  • Zhou H, Schwartz MR, Coffey D, Smith D, Mody DR, Ge Y. Should LSIL-H be a distinct cytology category?: A study on the frequency and distribution of 40 human papillomavirus genotypes in 808 women. Cancer Cytopathol. 2012 Dec 25;120(6):373-9.
  • Kim J, Coffey DM, Creighton CJ, Yu Z, Hawkins SM, Matzuk MM. High-grade serous ovarian cancer arises from fallopian tube in a mouse model. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3921-6.
  • Ozcan A, Liles N, Coffey D, Shen SS, Truong LD. PAX2 and PAX8 Expression in Primary and Metastatic Müllerian Epithelial Tumors: A Comprehensive Comparison. Am J Surg Pathol. 2011 Dec;35(12):1837-47.
  • Stancel GA, Coffey D, Alvarez K, Halks-Miller M, Lal A, Mody D, Koen T, Fairley T, Monzon FA. Identification of tissue of origin in body fluid specimens using a gene expression microarray assay. Cancer Cytopathol. 2011 Jun 29. [Epub ahead of print]
  • Ge Y, Ro JY, Kim D, Kim CH, Reardon MJ, Blackmon S, Zhai J, Coffey D, Benjamin RS, Ayala AG. Clinicopathologic and immunohistochemical characteristics of adult primary cardiac angiosarcomas: analysis of 10 cases. Ann Diagn Pathol. 2011 Aug;15(4):262-7.
  • Ozcan A, Shen SS, Hamilton C, Anjana K, Coffey D, Krishnan B, Truong LD. PAX 8 expression in non-neoplastic tissues, primary tumors, and metastatic tumors: a comprehensive immunohistochemical study. Mod Pathol. 2011 Jun;24(6):751-64.
  • Merritt WM, Kamat AA, Hwang JY, Bottsford-Miller J, Lu C, Lin YG, Coffey D, Spannuth W, Nugent E, Han LY, Landen CN, Nick AM, Stone RL, Coffman KT, Bruckheimer E, Broaddus R, Gershenson DM, Coleman RL, Sood AK. Clinical and biological impact of EphA2 overexpression and angiogenesis in endometrial cancer. Cancer Biol Ther. 2011 Jan 12;10(12):1306-14. 
  • Ozcan A, Zhai Q, Javed R, Shen SS, Coffey D, Krishnan B, Truong LD. PAX-2 Is a Helpful Marker for Diagnosing Metastatic Renal Cell Carcinoma: Comparison With the Renal Cell Carcinoma Marker Antigen and Kidney-Specific Cadherin. Arch Pathol Lab Med. 2010 Aug;134(8):1121-9.
  • Zhai QJ, Ozcan A, Hamilton C, Shen SS, Coffey D, Krishnan B, Truong LD. PAX-2 expression in non-neoplastic, primary neoplastic, and metastatic neoplastic tissue: A comprehensive immunohistochemical study. Appl Immunohistochem Mol Morphol. 2010 Jul;18(4):323-32.
  • Kamat AA, Coffey D, Merritt WM, Nugent E, Urbauer D, Lin YG, Edwards C, Broaddus R, Coleman RL, Sood AK. EphA2 overexpression is associated with lack of hormone receptor expression and poor outcome in endometrial cancer. Cancer. 2009 Jun 15;115(12):2684-92.
  • Kim CH, Dancer JY, Coffey D, Zhai QJ, Reardon M, Ayala AG, Ro JY. Clinicopathologic study of 24 patients with primary cardiac sarcomas: a 10-year single institution experience. Hum Pathol. 2008 Jun;39(6):933-8.
  • Lyons-Boudreaux V, Mody DR, Zhai J, Coffey D. Cytologic malignancy versus benignancy: how useful are the "newer" markers in body fluid cytology? Arch Pathol Lab Med. 2008 Jan;132(1):23-8.
  • Kamat AA, Merritt WM, Coffey D, Lin YG, Patel PR, Broaddus R, Nugent E, Han LY, Landen CN Jr, Spannuth WA, Lu C, Coleman RL, Gershenson DM, Sood AK. Clinical and biological significance of vascular endothelial growth factor in endometrial cancer. Clin Cancer Res. 2007 Dec 15;13(24):7487-95.
  • Coffey D, Kaplan AL, Ramzy I. Intraoperative consultation in gynecologic pathology. Arch Pathol Lab Med. 2005 Dec;129(12):1544-57. Review.
  • Kamat AA, Feng S, Agoulnik IU, Kheradmand F, Bogatcheva NV, Coffey D, Sood AK, Agoulnik AI. The role of relaxin in endometrial cancer. Cancer Biol Ther. 2006 Jan;5(1):71-7.