The Center for Neuroregeneration strives to discover groundbreaking therapies to improve the quality of life for people who suffer from disorders to the Central Nervous System. The Center is comprised of laboratories with expertise in neural stem cell biology, neural activity and stimulation, robotics, cell growth, myelin and the genetic regulation of plasticity.
The Neuroplasticity lab specializes in neural stem cell biology, neural activity and stimulation, robotics, cell growth, myelin and the genetic regulation of plasticity. Signature projects include a focus on restoration of locomotor and sensory function through neural stimulation and promotion of innate regenerative capacity through cell and gene therapy. Researchers have also harnessed the tools of cell engineering to create human neural circuits within experimental microenvironments to better model disease and produce neural replacement parts for repair of the brain and spinal cord.
The Astrocellular Therapeutics Lab is specifically focused on understanding the functional relationship of human neurons and astrocytes in normal and injured states. We employ novel three-dimensional human pluripotent stem cell-based culture techniques, electrophysiology, transplantations and molecular/biochemical approaches to regenerate neural cell types.
The Cerebrovascular Research Laboratory studies brain microcirculation in normal and pathological conditions. we employ various in vitro and in vivo techniques to better understand the intimate relations between the initial causes, the changes in microcirculation and the role of the latter in brain damage.
The Glioblastoma Research Lab is involved in diverse projects that address basic and translational biology of brain cancers, with a primary focus on glioblastoma (GBM). Our basic science interests revolve around the role of the Twist1 transcription factor as a regulator of epithelial mesenchymal transition (EMT) in GBM.
The Brain-Machine research group is led by Dr. Jose Luis Contreras-Vidal at the University of Houston Main Campus. The team is dedicated to the engineering of the brain, and the design of non-invasive brain-machine interface and robotic systems for rehabilitation, enhancement or repair of the motor system after brain or body injury, neurological insults, or advanced aging.