RESEARCH & clinical trials
Using the tools of human neuroimaging, including MRI, PET and EEG, the Neuroimaging Lab aims to clarify the neurobiology and improve the treatment of the following disorders causing cognitive impairment: Alzheimer’s, Frontotemporal dementia, Genetic underpinning of regional involvement patterns, Neuroimaging correlates of social cognition, Traumatic brain injury, Amyloid and tau imaging in acute and chronic concussion, Timing and brain localization of tau deposition in patients with repeated head trauma, Schizophrenia.
The Speech and Language Center of the Department of Neurology conducts basic neurophysiological studies in the songbird zebra finch, and functional magnetic resonance imaging (fMRI) and brain magnetic stimulation studies in humans. The songbird research pertains to the neurobiology of vocal learning and animal models of speech-motor disorders.
Peggy and Gary Edwards ALS Laboratory
Research in the Peggy and Gary Edwards ALS Laboratory focuses on developing new insights into degenerative neurologic diseases, with a primary emphasis on Amyotrophic Lateral Sclerosis (ALS). More specifically, the importance of immune/inflammatory alterations, as well as increased intracellular calcium and free-radical stress in ALS, Parkinson’s disease and Alzheimer’s disease.
Director: Stanley H. Appel, MD