Publications


MCL-1 depletion impairs DNA DSB repair and re-initiation of stalled DNA replication forks;
Mattoo, AR, Pandita, RK, Chakraborty, S, Charaka, V, Mujoo, K, Hunt, CR & Pandita, TK 2016, Molecular and Cellular Biology. DOI:

Defective cholesterol metabolism in amyotrophic lateral sclerosis;
Abdel-Khalik, J, Yutuc, E, Crick, PJ, Gustafsson, J-Å, Warner, M, Roman, G, Talbot, K, Gray, E, Griffiths, WJ, Turner, MR & Wang, Y 2016, Journal of Lipid Research. DOI:

Regulation of oxidized base damage repair by chromatin assembly factor 1 subunit A;
Yang, C , Sengupta, S, Hegde, PM, Mitra, J, Jiang, S, Holey, B, Sarker, AH, Tsai, M-S, Hegde, ML & Mitra, S 2016, Nucleic acids research. DOI:

Oxidized Guanine Base Lesions Function in 8-Oxoguanine DNA Glycosylase1-Mediated Epigenetic Regulation of Nuclear Factor kappaB-Driven Gene Expression;
Pan, L, Zhu, B, Hao, W, Zeng, X, Vlahopoulos, SA, Hazra, TK, Hegde, ML, Radak, Z, Bacsi, A, Brasier, AR, Ba, X & Boldogh, I 2016, The Journal of biological chemistry. DOI:

TDP-43/FUS in motor neuron disease: Complexity and challenges;
Guerrero, EN, Wang, H, Mitra, J, Hegde, PM, Stowell, SE, Liachko, NF, Kraemer, BC, Garruto, RM, Rao, KS & Hegde, ML 2016, Progress in Neurobiology, vol 145-146, pp. 78-97. DOI:

TDP-43/FUS in motor neuron disease: Complexity and challenges;
Guerrero, EN, Wang, H, Mitra, J, Hegde, PM, Stowell, SE, Liachko, NF, Kraemer, BC, Garruto, RM, Rao, KS & Hegde, ML 2016, Progress in Neurobiology, vol 145-146, pp. 78-97. DOI:

A robust, good manufacturing practice–compliant, clinical-scale procedure to generate regulatory T cells from patients with amyotrophic lateral sclerosis for adoptive cell therapy;
Alsuliman, A, Appel, SH, Beers, DR, Basar, R, Shaim, H, Kaur, I, Zulovich, J, Yvon, E, Muftuoglu, M, Imahashi, N, Kondo, K, Liu, E, Shpall, EJ & Rezvani, K 2016, Cytotherapy, vol 18, no. 10, pp. 1312-1324. DOI:

ATXN2-AS, a gene antisense to ATXN2, is associated with spinocerebellar ataxia type 2 and amyotrophic lateral sclerosis;
Li, PP, Sun, X, Xia, G, Arbez, N, Paul, S, Zhu, S, Peng, HB, Ross, CA, Koeppen, AH, Margolis, RL, Pulst, SM, Ashizawa, T & Rudnicki, DD 2016, Annals of Neurology, vol 80, no. 4, pp. 600-615. DOI:

ATXN2-AS, a gene antisense to ATXN2, is associated with spinocerebellar ataxia type 2 and amyotrophic lateral sclerosis;
Li, PP, Sun, X, Xia, G, Arbez, N, Paul, S, Zhu, S, Peng, HB, Ross, CA, Koeppen, AH, Margolis, RL, Pulst, SM, Ashizawa, T & Rudnicki, DD 2016, Annals of Neurology, vol 80, no. 4, pp. 600-615. DOI:

A robust, good manufacturing practice–compliant, clinical-scale procedure to generate regulatory T cells from patients with amyotrophic lateral sclerosis for adoptive cell therapy;
Alsuliman, A, Appel, SH, Beers, DR, Basar, R, Shaim, H, Kaur, I, Zulovich, J, Yvon, E, Muftuoglu, M, Imahashi, N, Kondo, K, Liu, E, Shpall, EJ & Rezvani, K 2016, Cytotherapy, vol 18, no. 10, pp. 1312-1324. DOI: