Publications


The isolation and characterization of CTC subsets related to breast cancer dormancy
Vishnoi, M, Peddibhotla, S, Yin, W, Scamardo, AT, George, GC, Hong, DS & Marchetti, D 2015, Scientific reports, vol 5, 17533. DOI:

Oncogenic role of Merlin/NF2 in glioblastoma
Guerrero, PA, Yin, W, Camacho, L & Marchetti, D 2015, Oncogene, vol 34, no. 20, pp. 2621-30. DOI:

Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes
Caruana, I, Savoldo, B, Hoyos, V, Weber, G, Liu, H, Kim, ES, Ittmann, MM, Marchetti, D & Dotti, G 2015, Nature Medicine, vol 21, no. 5, pp. 524-529. DOI:

Heparanase mediates a novel mechanism in lapatinib-resistant brain metastatic breast cancer
Zhang, L, Ngo, JA, Wetzel, MD & Marchetti, D 2015, Neoplasia (United States), vol 17, no. 1, pp. 101-113. DOI:

MicroRNA and Protein Profiling of Brain Metastasis Competent Cell-Derived Exosomes
Camacho, L, Guerrero, P & Marchetti, D 2013, PLoS ONE, vol 8, no. 9, e73790. DOI:

The identification and characterization of breast cancer CTCs competent for brain metastasis
Zhang, L, Ridgway, LD, Wetzel, MD, Ngo, J, Yin, W, Kumar, D, Goodman, JC, Groves, MD & Marchetti, D 2013, Science Translational Medicine, vol 5, no. 180, 180ra48. DOI:

Heparanase-induced GEF-H1 signaling regulates the cytoskeletal dynamics of brain metastatic breast cancer cells
Ridgway, LD, Wetzel, MD, Ngo, JA, Erdreich-Epstein, A & Marchetti, D 2012, Molecular Cancer Research, vol 10, no. 6, pp. 689-702. DOI:

Selection of brain metastasis-initiating breast cancer cells determined by growth on hard agar
Guo, L, Fan, D, Zhang, F, Price, JE, Lee, JS, Marchetti, D, Fidler, IJ & Langley, RR 2011, American Journal of Pathology, vol 178, no. 5, pp. 2357-2366. DOI:

Heparanase modulates Shh and Wnt3a signaling in human medulloblastoma cells
Ridgway, LD, Wetzel, MD & Marchetti, D 2011, Experimental and Therapeutic Medicine, vol 2, no. 2, pp. 229-237. DOI:

MicroRNA-1258 suppresses breast cancer brain metastasis by targeting heparanase
Zhang, L, Sullivan, PS, Goodman, JC, Gunaratne, PH & Marchetti, D 2011, Cancer Research, vol 71, no. 3, pp. 645-654. DOI:

Modulation of GEF-H1 induced signaling by heparanase in brain metastatic melanoma cells
Ridgway, LD, Wetzel, MD & Marchetti, D 2010, Journal of Cellular Biochemistry, vol 111, no. 5, pp. 1299-1309. DOI:

Epidermal growth factor-induced heparanase nucleolar localization augments DNA topoisomerase I activity in brain metastatic breast cancer
Zhang, L, Sullivan, P, Suyama, J & Marchetti, D 2010, Molecular Cancer Research, vol 8, no. 2, pp. 278-290. DOI:

Cell surface heparan sulfate released by Heparanase promotes melanoma cell migration and angiogenesis
Roy, M & Marchetti, D 2009, Journal of Cellular Biochemistry, vol 106, no. 2, pp. 200-209. DOI:

HIP/RPL29 antagonizes VEGF and FGF2 stimulated angiogenesis by interfering with HS-dependent responses
DSouza, S, Yang, W, Marchetti, D, Muir, C, Farach-Carson, MC & Carson, DD 2008, Journal of Cellular Biochemistry, vol 105, no. 5, pp. 1183-1193. DOI:

Heparanase expression and activity influences chondrogenic and osteogenic processes during endochondral bone formation
Brown, AJ, Alicknavitch, M, DSouza, SS, Daikoku, T, Kirn-Safran, CB, Marchetti, D, Carson, DD & Farach-Carson, MC 2008, Bone, vol 43, no. 4, pp. 689-699. DOI:

Neurotrophin receptors and heparanase: A functional axis in human medulloblastoma invasion
Marchetti, D, Mrak, RE, Paulsen, DD & Sinnappah-Kang, ND 2007, Journal of Experimental and Clinical Cancer Research, vol 26, no. 1, pp. 5-23.

Biocatalytic and antimetastatic studies of the marine cembranoids sarcophine and 2-epi-16-deoxysarcophine
Sawant, SS, Youssef, DTA, Reiland, J, Ferniz, M, Marchetti, D & El Sayed, KA 2006, Journal of Natural Products, vol 69, no. 7, pp. 1010-1013. DOI:

Heparanase expression and TrkC/p75NTR ratios in human medulloblastoma
Sinnappah-Kang, ND, Mrak, RE, Paulsen, DB & Marchetti, D 2006, Clinical and Experimental Metastasis, vol 23, no. 1, pp. 55-63. DOI:

HPSE-1 expression and functionality in differentiating neural cells
Moretti, M, Sinnappah-Kang, ND, Toller, M, Curcio, F & Marchetti, D 2006, Journal of Neuroscience Research, vol 83, no. 4, pp. 694-701. DOI:

Heparanase mechanisms of melanoma metastasis to the brain: Development and use of a brain slice model
Murry, BP, Blust, BE, Singh, A, Foster, TP & Marchetti, D 2006, Journal of Cellular Biochemistry, vol 97, no. 2, pp. 217-225. DOI: