Publications


Molecular characterization of breast cancer CTCs associated with brain metastasis
Boral, D, Vishnoi, M, Liu, HN, Yin, W, Sprouse, ML, Scamardo, A, Hong, DS, Tan, TZ, Thiery, JP, Chang, JC & Marchetti, D 2017, Nature Communications, vol 8, no. 1, 196. DOI:

Molecular characterization of breast cancer CTCs associated with brain metastasis
Boral, D, Vishnoi, M, Liu, HN, Yin, W, Sprouse, ML, Scamardo, A, Hong, DS, Tan, TZ, Thiery, JP, Chang, JC & Marchetti, D 2017, Nature Communications, vol 8, no. 1, 196. DOI:

The isolation and characterization of CTC subsets related to breast cancer dormancy
Vishnoi, M, Peddibhotla, S, Yin, W, Scamardo, AT, George, GC, Hong, DS & Marchetti, D 2015, Scientific reports, vol 5, 17533. DOI:

Oncogenic role of Merlin/NF2 in glioblastoma
Guerrero, PA, Yin, W, Camacho, L & Marchetti, D 2015, Oncogene, vol 34, no. 20, pp. 2621-30. DOI:

Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes
Caruana, I, Savoldo, B, Hoyos, V, Weber, G, Liu, H, Kim, ES, Ittmann, MM, Marchetti, D & Dotti, G 2015, Nature Medicine, vol 21, no. 5, pp. 524-529. DOI:

Heparanase mediates a novel mechanism in lapatinib-resistant brain metastatic breast cancer
Zhang, L, Ngo, JA, Wetzel, MD & Marchetti, D 2015, Neoplasia (United States), vol 17, no. 1, pp. 101-113. DOI:

MicroRNA and Protein Profiling of Brain Metastasis Competent Cell-Derived Exosomes
Camacho, L, Guerrero, P & Marchetti, D 2013, PLoS ONE, vol 8, no. 9, e73790. DOI:

The identification and characterization of breast cancer CTCs competent for brain metastasis
Zhang, L, Ridgway, LD, Wetzel, MD, Ngo, J, Yin, W, Kumar, D, Goodman, JC, Groves, MD & Marchetti, D 2013, Science Translational Medicine, vol 5, no. 180, 180ra48. DOI:

Heparanase-induced GEF-H1 signaling regulates the cytoskeletal dynamics of brain metastatic breast cancer cells
Ridgway, LD, Wetzel, MD, Ngo, JA, Erdreich-Epstein, A & Marchetti, D 2012, Molecular Cancer Research, vol 10, no. 6, pp. 689-702. DOI:

Selection of brain metastasis-initiating breast cancer cells determined by growth on hard agar
Guo, L, Fan, D, Zhang, F, Price, JE, Lee, JS, Marchetti, D, Fidler, IJ & Langley, RR 2011, American Journal of Pathology, vol 178, no. 5, pp. 2357-2366. DOI:

Heparanase modulates Shh and Wnt3a signaling in human medulloblastoma cells
Ridgway, LD, Wetzel, MD & Marchetti, D 2011, Experimental and Therapeutic Medicine, vol 2, no. 2, pp. 229-237. DOI:

MicroRNA-1258 suppresses breast cancer brain metastasis by targeting heparanase
Zhang, L, Sullivan, PS, Goodman, JC, Gunaratne, PH & Marchetti, D 2011, Cancer Research, vol 71, no. 3, pp. 645-654. DOI:

Modulation of GEF-H1 induced signaling by heparanase in brain metastatic melanoma cells
Ridgway, LD, Wetzel, MD & Marchetti, D 2010, Journal of Cellular Biochemistry, vol 111, no. 5, pp. 1299-1309. DOI:

Epidermal growth factor-induced heparanase nucleolar localization augments DNA topoisomerase I activity in brain metastatic breast cancer
Zhang, L, Sullivan, P, Suyama, J & Marchetti, D 2010, Molecular Cancer Research, vol 8, no. 2, pp. 278-290. DOI:

Cell surface heparan sulfate released by Heparanase promotes melanoma cell migration and angiogenesis
Roy, M & Marchetti, D 2009, Journal of Cellular Biochemistry, vol 106, no. 2, pp. 200-209. DOI:

HIP/RPL29 antagonizes VEGF and FGF2 stimulated angiogenesis by interfering with HS-dependent responses
DSouza, S, Yang, W, Marchetti, D, Muir, C, Farach-Carson, MC & Carson, DD 2008, Journal of Cellular Biochemistry, vol 105, no. 5, pp. 1183-1193. DOI:

Heparanase expression and activity influences chondrogenic and osteogenic processes during endochondral bone formation
Brown, AJ, Alicknavitch, M, DSouza, SS, Daikoku, T, Kirn-Safran, CB, Marchetti, D, Carson, DD & Farach-Carson, MC 2008, Bone, vol 43, no. 4, pp. 689-699. DOI:

Neurotrophin receptors and heparanase: A functional axis in human medulloblastoma invasion
Marchetti, D, Mrak, RE, Paulsen, DD & Sinnappah-Kang, ND 2007, Journal of Experimental and Clinical Cancer Research, vol 26, no. 1, pp. 5-23.

Biocatalytic and antimetastatic studies of the marine cembranoids sarcophine and 2-epi-16-deoxysarcophine
Sawant, SS, Youssef, DTA, Reiland, J, Ferniz, M, Marchetti, D & El Sayed, KA 2006, Journal of Natural Products, vol 69, no. 7, pp. 1010-1013. DOI:

Heparanase expression and TrkC/p75NTR ratios in human medulloblastoma
Sinnappah-Kang, ND, Mrak, RE, Paulsen, DB & Marchetti, D 2006, Clinical and Experimental Metastasis, vol 23, no. 1, pp. 55-63. DOI: