Li lab Publications


Pet Imaging and its Application in Cardiovascular Diseases
Li, Z , Gupte, AA, Zhang, A & Hamilton, DJ 2017, Houston Methodist DeBakey Cardiovascular Journal, vol 13, no. 1, pp. 29-33. DOI:

Prediction and Early Evaluation of Anticancer Therapy Response: From Imaging of Drug Efflux Pumps to Targeted Therapy Response
Menga, Q, Li, Z & Li, S 2016, Current Medicinal Chemistry, vol 23, no. 41, pp. 4625-4638. DOI:

Structure-Based Design of Potent Nicotinamide Phosphoribosyltransferase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities
Bai, J, Liao, C, Liu, Y, Qin, X, Chen, J, Qiu, Y, Qin, D, Li, Z, Tu, ZC & Jiang, S 2016, Journal of Medicinal Chemistry, vol 59, no. 12, pp. 5766-5779. DOI:

Discovery of Novel Class i Histone Deacetylase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities
Yao, Y, Tu, Z, Liao, C, Wang, Z, Li, S, Yao, H, Li, Z & Jiang, S 2015, Journal of Medicinal Chemistry, vol 58, no. 19, pp. 7672-7680. DOI:

Unprecedented reactions:: from epichlorohydrin to epoxyglycidyl substituted divinyl ether and its conversion into epoxyglycidyl propargyl ether
Yao, Y, Li, Z, Qiu, Y, Bai, J, Su, J, Zhang, D & Jiang, S 2015, Scientific reports, vol 5, 14231. DOI:

An HDAC-Targeted Imaging Probe LBH589-Cy5.5 for Tumor Detection and Therapy Evaluation
Meng, Q, Liu, Z, Li, F, Ma, J, Wang, H, Huan, Y & Li, Z 2015, Molecular Pharmaceutics, vol 12, no. 7, pp. 2469-2476. DOI:

One-step 18F labeling of non-peptidic bivalent integrin avß3 antagonist for cancer imaging
Wang, W, Liu, Z & Li, Z 2015, Bioconjugate Chemistry, vol 26, no. 1, pp. 24-28. DOI:

An HDAC-Targeted Near-Infrared Probe LBH589-Cy5.5 for Tumor Detection and Therapy Evaluation
Li, Z 2015, Molecular Pharmacology, vol 12, no. 7, pp. 2469-76.

Design, synthesis, and biological evaluation of 1, 3-disubstituted-pyrazole derivatives as new class I and IIb histone deacetylase inhibitors
Yao, Y, Liao, C, Li, Z, Wang, Z, Sun, Q, Liu, C, Yang, Y, Tu, Z & Jiang, S 2014, European Journal of Medicinal Chemistry, vol 86, pp. 639-652. DOI:

Specific and sensitive tumor imaging using biostable oligonucleotide aptamer probes
Zeng, Z, Parekh, P, Li, Z, Shi, Z-Z, Tung, C-H & Zu, Y 2014, Theranostics, vol 4, no. 9, pp. 945-52. DOI:

Biological evaluation of new mimetics of annonaceous acetogenins: Alteration of right scaffold by click linkage with aromatic functionalities
Liu, Y, Xiao, Q, Liu, Y, Li, Z, Qiu, Y, Zhou, GB, Yao, ZJ & Jiang, S 2014, European Journal of Medicinal Chemistry, vol 78, pp. 248-258. DOI:

Identification of novel bivalent mimetics of annonaceous acetogenins via a scaffold-hopping strategy
Liu, Y, Liu, Y, Li, Z, Zhou, GB, Yao, ZJ & Jiang, S 2014, Bioorganic and Medicinal Chemistry Letters, vol 24, no. 7, pp. 1650-1653. DOI:

A tyrosine kinase inhibitor-based high-affinity PET radiopharmaceutical targets vascular endothelial growth factor receptor
Li, F, Jiang, S, Zu, Y, Lee, DY & Li, Z 2014, Journal of Nuclear Medicine, vol 55, no. 9, pp. 1525-1531. DOI:

Molecular imaging in tracking tumor-specific Cytotoxic T Lymphocytes (CTLs)
Liu, Z & Li, Z 2014, Theranostics, vol 4, no. 10, pp. 990-1001. DOI:

Biological evaluation of 2-methylpyrimidine derivatives as active pan Bcr-Abl inhibitors
Zou, D, Qiu, Y, Tu, Z, Liao, C, Luo, J, Meng, Q, Yao, R, Li, Z & Jiang, S 2014, Science China Chemistry, vol 57, no. 6, pp. 823-832. DOI:

Specific binding of modified ZD6474 (Vandetanib) monomer and its dimer with VEGF receptor-2
Kim, YS, Li, F, Oneill, BE & Li, Z 2013, Bioconjugate Chemistry, vol 24, no. 11, pp. 1937-1944. DOI:

Multivalency of non-peptide integrin avß3 antagonist slows tumor growth
Kim, YS, Li, F, Kong, R, Bai, Y, Li, KCP, Fan, Y, ONeill, BE & Li, Z 2013, Molecular Pharmaceutics, vol 10, no. 10, pp. 3603-3611. DOI:

Novel 64Cu-labeled CUDC-101 for in vivo PET imaging of histone deacetylases
Meng, Q, Li, F, Jiang, S & Li, Z 2013, ACS Medicinal Chemistry Letters, vol 4, no. 9, pp. 858-862. DOI:

Molecular imaging probes for diagnosis and therapy evaluation of breast cancer
Meng, Q & Li, Z 2013, International Journal of Biomedical Imaging, vol 2013, 230487. DOI:

Biological evaluation of new largazole analogues: Alteration of macrocyclic scaffold with click chemistry
Li, X, Tu, Z, Li, H, Liu, C, Li, Z, Sun, Q, Yao, Y, Liu, J & Jiang, S 2013, ACS Medicinal Chemistry Letters, vol 4, no. 1, pp. 132-136. DOI: