Publications


MCL-1 depletion impairs DNA DSB repair and re-initiation of stalled DNA replication forks;
Mattoo, AR, Pandita, RK, Chakraborty, S, Charaka, V, Mujoo, K, Hunt, CR & Pandita, TK 2016, Molecular and Cellular Biology. DOI:

Bromodomain and extraterminal protein inhibition blocks growth of triple-negative breast cancers through the suppression of Aurora kinases;
Sahni, JM, Gayle, SS, Bonk, KLW, Vite, LC, Yori, JL, Webb, B, Ramos, EK, Seachrist, DD, Landis, MD, Chang, JC, Bradner, JE & Keri, RA 2016, Journal of Biological Chemistry, vol 291, no. 45, pp. 23756-23768. DOI:

The pivotal role of mammalian target of rapamycin inhibition in the treatment of patients with neuroendocrine tumors;
Phan, AT & Dave, B 2016, Cancer Medicine, vol 5, no. 10, pp. 2953-2964. DOI:

A robust, good manufacturing practice–compliant, clinical-scale procedure to generate regulatory T cells from patients with amyotrophic lateral sclerosis for adoptive cell therapy;
Alsuliman, A, Appel, SH, Beers, DR, Basar, R, Shaim, H, Kaur, I, Zulovich, J, Yvon, E, Muftuoglu, M, Imahashi, N, Kondo, K, Liu, E, Shpall, EJ & Rezvani, K 2016, Cytotherapy, vol 18, no. 10, pp. 1312-1324. DOI:

A robust, good manufacturing practice–compliant, clinical-scale procedure to generate regulatory T cells from patients with amyotrophic lateral sclerosis for adoptive cell therapy;
Alsuliman, A, Appel, SH, Beers, DR, Basar, R, Shaim, H, Kaur, I, Zulovich, J, Yvon, E, Muftuoglu, M, Imahashi, N, Kondo, K, Liu, E, Shpall, EJ & Rezvani, K 2016, Cytotherapy, vol 18, no. 10, pp. 1312-1324. DOI:

Aspiration Thrombectomy after Intravenous Alteplase Versus Intravenous Alteplase Alone;
Mocco, J, Zaidat, OO, Von Kummer, R, Yoo, AJ, Gupta, R, Lopes, D, Frei, D, Shownkeen, H, Budzik, R, Ajani, ZA, Grossman, A, Altschul, D, McDougall, C, Blake, L, Fitzsimmons, BF, Yavagal, D, Terry, J, Farkas, J, Lee, SK, Baxter, B, Wiesmann, M, Knauth, M, Heck, D, Hussain, S, Chiu, D, Alexander, MJ, Malisch, T, Kirmani, J, Miskolczi, L & Khatri, P 2016, Stroke, vol 47, no. 9, pp. 2331-2338. DOI:

Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq;
Mann, KM, Newberg, JY, Black, MA, Jones, DJ, Amaya-Manzanares, F, Guzman-Rojas, L, Kodama, T, Ward, JM, Rust, AG, Van Der Weyden, L, Yew, CCK, Waters, JL, Leung, ML, Rogers, K, Rogers, SM, Mcnoe, LA, Selvanesan, L, Navin, N, Jenkins, NA, Copeland, NG & Mann, MB 2016, Nature Biotechnology, vol 34, no. 9, pp. 962-972. DOI:

HOXC10 expression supports the development of chemotherapy resistance by fine tuning DNA repair in breast cancer cells;
Sadik, H, Korangath, P, Nguyen, NK, Gyorffy, B, Kumar, R, Hedayati, M, Teo, WW, Park, S, Panday, H, Munoz, TG, Menyhart, O, Shah, N, Pandita, RK, Chang, JC, DeWeese, T, Chang, HY, Pandita, TK & Sukumar, S 2016, Cancer Research, vol 76, no. 15, pp. 4443-4456. DOI:

Stem cells in amyotrophic lateral sclerosis: Ready for prime time?;
Appel, SH & Armon, C 2016, Neurology, vol 87, no. 4, pp. 348-349. DOI:

A recellularized human colon model identifies cancer driver genes;
Chen, HJ, Wei, Z, Sun, J, Bhattacharya, A, Savage, DJ, Serda, R, Mackeyev, Y, Curley, SA, Bu, P, Wang, L, Chen, S, Cohen-Gould, L, Huang, E, Shen, X, Lipkin, SM, Copeland, NG, Jenkins, NA & Shuler, ML 2016, Nature Biotechnology, vol 34, no. 8, pp. 845-851. DOI: